1,1,2-Trichloroethane
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Names | |||
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Preferred IUPAC name 1,1,2-Trichloroethane | |||
Other names 1,1,2-TCA vinyl trichloride symmetrical Trichloroethane monochlorethylen chloride (archaic) | |||
Identifiers | |||
CAS Number |
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3D model (JSmol) |
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ChEBI |
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ChEMBL |
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ChemSpider |
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ECHA InfoCard | 100.001.061 | ||
KEGG |
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PubChem CID |
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UNII |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |||
Chemical formula | C2H3Cl3 | ||
Molar mass | 133.40 g/mol | ||
Appearance | colorless liquid[1] | ||
Odor | sweet, chloroform-like[1] (in high concentrations) | ||
Density | 1.435 g/cm3 | ||
Melting point | −37 °C (−35 °F; 236 K) | ||
Boiling point | 110 to 115 °C (230 to 239 °F; 383 to 388 K) | ||
Solubility in water | 0.4% (20°C)[1] | ||
Vapor pressure | 19 mmHg (20°C)[1] | ||
Hazards | |||
NFPA 704 (fire diamond) | 3 1 | ||
Explosive limits | 6–15.5%[1] | ||
Lethal dose or concentration (LD, LC): | |||
LD50 (median dose) | 1200 mg/kg (rat, orally)[2] | ||
LCLo (lowest published) | 13,100 mg/m3 (cat, 4.5 hr) 2000 ppm (rat, 4 hr)[3] | ||
NIOSH (US health exposure limits): | |||
PEL (Permissible) | TWA 10 ppm (45 mg/m3) [skin][1] | ||
REL (Recommended) | Ca TWA 10 ppm (45 mg/m3) [skin][1] | ||
IDLH (Immediate danger) | Ca [100 ppm][1] | ||
Related compounds | |||
Related compounds | 1,1,1-Trichloroethane; Trichloroethylene | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references |
1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula C2H3Cl3 and the structural formula CH2Cl—CHCl2. It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture.
It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene.[4]
Toxicity
1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness.[5]
The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-Trichloroethane at 10 ppm over an eight-hour time-weighted average.[6]
References
- ^ a b c d e f g h NIOSH Pocket Guide to Chemical Hazards. "#0628". National Institute for Occupational Safety and Health (NIOSH).
- ^ 1,1,2-Trichloroethane toxicity
- ^ "1,1,2-Trichloroethane". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
- ^ Toxicological profile for 1,1,2-trichloroethane (PDF) (Report). Agency for Toxic Substances and Disease Registry (ATSDR). March 2021. Archived (PDF) from the original on 2022-03-05. Retrieved 2023-08-23.
- ^ "Safety (MSDS) data for 1,1,2-trichloroethane" (PDF).
- ^ CDC - NIOSH Pocket Guide to Chemical Hazards
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