1-Decanol
![]() | |
![]() | |
Names | |
---|---|
Preferred IUPAC name Decan-1-ol | |
Other names decyl alcohol n-decyl alcohol capric alcohol epal 10 antak agent 504 | |
Identifiers | |
CAS Number |
|
3D model (JSmol) |
|
ChEBI |
|
ChEMBL |
|
ChemSpider |
|
ECHA InfoCard | 100.003.597 ![]() |
KEGG |
|
PubChem CID |
|
UNII |
|
CompTox Dashboard (EPA) |
|
InChI
| |
| |
Properties | |
Chemical formula | C10H21OH |
Molar mass | 158.28 g/mol |
Appearance | Viscous liquid |
Density | 0.8297 g/cm3 |
Melting point | 6.4 °C (43.5 °F; 279.5 K) |
Boiling point | 232.9 °C (451.2 °F; 506.0 K) |
Solubility in water | 37 mg/L at 20°C[2] |
log P | 4.57 |
Viscosity | 12.048 mPa.s (@ 25 °C) |
Hazards | |
Flash point | 108 °C (226 °F; 381 K) |
Safety data sheet (SDS) | Oxford MSDS |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ![]() ![]() ![]() Infobox references |
1-Decanol is a straight chain fatty alcohol with ten carbon atoms and the molecular formula C10H21OH. It is a colorless to light yellow viscous liquid that is insoluble in water and has an aromatic odor.[3] The interfacial tension against water at 20 °C is 8.97 mN/m.
Production
Decanol can be prepared by the hydrogenation of decanoic acid, which occurs in modest quantities in coconut oil (about 10%) and palm kernel oil (about 4%). It may also be produced synthetically via the Ziegler process.
Uses
Decanol is used in the manufacture of plasticizers, lubricants, surfactants and solvents. Its ability to permeate the skin has led to it being investigated as a penetration enhancer for transdermal drug delivery.[4][5]
Safety
Like other medium chain fatty alcohols, 1-decanol is able to permeate the skin which can lead to irritation.
References
- ^ Merck Index, 12th Edition, 2911.
- ^ "1-Decanol".
- ^ "Material Safety Data Sheet - Decyl alcohol, 99%". fscimage.fishersci.com. Archived from the original on 2021-09-01. Retrieved 2021-09-01.
- ^ Kanikkannan, N; Singh, Mandip (November 2002). "Skin permeation enhancement effect and skin irritation of saturated fatty alcohols". International Journal of Pharmaceutics. 248 (1–2): 219–228. doi:10.1016/S0378-5173(02)00454-4. PMID 12429475.
- ^ Williams, Adrian C; Barry, Brian W (March 2004). "Penetration enhancers". Advanced Drug Delivery Reviews. 56 (5): 603–618. doi:10.1016/j.addr.2003.10.025. PMID 15019749.
- v
- t
- e
Alcohols found in alcoholic drinks |
|
---|---|
Medical alcohol |
|
Toxic alcohols |
alcohols (1°)
Methanol | |
---|---|
Ethanol |
|
Butanol |
|
Straight-chain saturated C1 — C9 |
|
Straight-chain saturated C10 — C19 |
|
Straight-chain saturated C20 — C29 |
|
Straight-chain saturated C30 — C39 |
|
Straight-chain saturated C40 — C49 |
|
alcohols (2°)
alcohols (3°)
- 2-Methyl-2-pentanol
- 2-Methylheptan-2-ol
- 2-Methylhexan-2-ol
- 3-Methyl-3-pentanol
- 3-Methyloctan-3-ol
- Diacetone alcohol
- Ethchlorvynol
- Methylpentynol
- Nonafluoro-tert-butyl alcohol
- tert-Amyl alcohol
- tert-Butyl alcohol
- Triphenylethanol
- Triphenylmethanol
Monohydric alcohols |
|
---|---|
Dihydric alcohols | |
Trihydric alcohols | |
Polyhydric alcohols (sugar alcohols) |
|
fatty alcohols
unsaturated
fatty alcohols
- 3-Methyl-3-pentanol
- Erucyl alcohol
- Linolenyl alcohol
- Linoleyl alcohol
- Oleyl alcohol
- Palmitoleyl alcohol
- tert-Amyl alcohol
- tert-Butyl alcohol
C1 — C7 |
|
---|---|
Deoxy sugar alcohols | |
Cyclic sugar alcohols | |
Glycylglycitols |
Monoterpene alcohols | |
---|---|
Sesquiterpene alcohols | |
Diterpene alcohols |
- 1,3-Difluoro-2-propanol
- 2,2,2-Trifluoroethanol
- 2-Fluoroethanol
- Nonafluoro-tert-butyl alcohol
- Trifluoromethanol
Category