2-Iodomelatonin
Chemical compound
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Formula | C13H15IN2O2 |
Molar mass | 358.179 g·mol−1 |
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2-Iodomelatonin is a melatonin analog used as a radiolabelled ligand for the melatonin receptors, MT1, MT2, and MT3. It acts as a full agonist at both MT1 and MT2 receptors.[1]
References
- ^ Audinot V, Mailliet F, Lahaye-Brasseur C, Bonnaud A, Le Gall A, Amossé C, Dromaint S, Rodriguez M, Nagel N, Galizzi JP, Malpaux B, Guillaumet G, Lesieur D, Lefoulon F, Renard P, Delagrange P, Boutin JA (June 2003). "New selective ligands of human cloned melatonin MT1 and MT2 receptors". Naunyn-Schmiedeberg's Arch Pharmacol. 367 (6): 553–61. doi:10.1007/s00210-003-0751-2. PMID 12764576. S2CID 20279702.
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Melatonin receptor modulators
- Agonists: 2-Iodomelatonin
- 6-Hydroxymelatonin
- Agomelatine
- Fabomotizole (afobazole)
- GR-196,429
- Melatonin
- N-Acetylserotonin (normelatonin)
- Piromelatine
- Ramelteon
- Tasimelteon
- TIK-301 (LY-156,735)
- Antagonists: Luzindole
- Agonists: 2-Iodomelatonin
- 6-Hydroxymelatonin
- Agomelatine
- GR-196,429
- Melatonin
- N-Acetylserotonin (normelatonin)
- Piromelatine
- Ramelteon
- Tasimelteon
- TIK-301 (LY-156,735)
- Antagonists: Luzindole
- Agonists: 2-Phenylmelatonin
- 5-Methoxyluzindole
- 6-Chloromelatonin
- 6-Fluoromelatonin
- 6-Methoxymelatonin
- 6,7-Dichloro-2-methylmelatonin
- 8-M-PDOT
- AMMTC
- GR-135,531 (of MT3Tooltip melatonin receptor 1C)
- N-Acetyltryptamine
- N-Butanoylmelatonin
- N-Propionylmelatonin
- S-24268
- S-25150
- Antagonists: 4-P-ADOT
- 4-P-PDOT
- DH-97
- N-Acetyltryptamine (of MT3)
- Prazosin (of MT3)
- S-20928
- S-22153
- S-24601
- S-25567
- S-26131
- See also: Receptor/signaling modulators
- Adrenergics
- Dopaminergics
- Serotonergics
- Monoamine metabolism modulators
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