HACD2 |
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Identifiers |
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Aliases | HACD2, PTPLB, 3-hydroxyacyl-CoA dehydratase 2 |
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External IDs | OMIM: 615939; MGI: 1918007; HomoloGene: 23409; GeneCards: HACD2; OMA:HACD2 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3q21.1 | Start | 123,490,820 bp[1] |
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End | 123,585,053 bp[1] |
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Gene location (Mouse) |
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![Chromosome 16 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/2/28/Ideogram_house_mouse_chromosome_16.svg/260px-Ideogram_house_mouse_chromosome_16.svg.png) | Chr. | Chromosome 16 (mouse)[2] |
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| Band | 16|16 B3 | Start | 34,842,798 bp[2] |
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End | 34,929,547 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gingival epithelium
- external globus pallidus
- vulva
- jejunal mucosa
- skin of thigh
- skin of hip
- endothelial cell
- mucosa of colon
- mucosa of sigmoid colon
- human penis
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| Top expressed in | - right kidney
- tail of embryo
- lip
- yolk sac
- genital tubercle
- zygote
- esophagus
- granulocyte
- embryo
- embryo
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - protein tyrosine phosphatase activity
- enzyme binding
- 3-hydroxyacyl-CoA dehydratase activity
- protein binding
- lyase activity
- 3R-hydroxyacyl-CoA dehydratase activity
- 3-hydroxy-behenoyl-CoA dehydratase activity
- 3-hydroxy-lignoceroyl-CoA dehydratase activity
- 3-hydroxy-arachidoyl-CoA dehydratase activity
- very-long-chain 3-hydroxyacyl-CoA dehydratase activity
| Cellular component | - integral component of membrane
- endoplasmic reticulum membrane
- endoplasmic reticulum
- membrane
- integral component of endoplasmic reticulum membrane
| Biological process | - fatty acid elongation
- fatty acid biosynthetic process
- sphingolipid biosynthetic process
- long-chain fatty-acyl-CoA biosynthetic process
- very long-chain fatty acid biosynthetic process
- fatty acid metabolic process
- lipid metabolism
- peptidyl-tyrosine dephosphorylation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001329783 NM_001329784 NM_001329786 NM_001329787 NM_198402 |
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RefSeq (protein) | |
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NP_001316712 NP_001316713 NP_001316715 NP_001316716 NP_940684 |
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Location (UCSC) | Chr 3: 123.49 – 123.59 Mb | Chr 16: 34.84 – 34.93 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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