Action - Assassin's Creed: Brotherhood – Ubisoft Montreal/Ubisoft
| Social Network Game |
Artistic Achievement | Sports |
| Story - Heavy Rain – David Cage, Quantic Dream/Sony Computer Entertainment
- Alan Wake – Sam Lake, Mikko Rautalahti, Petri Järvilehto, Remedy Entertainment/Microsoft Game Studios
- BioShock 2 – Jordan Thomas, 2K Marin/2K Games
- Call of Duty: Black Ops – Craig Houston, Dave Anthony, David S. Goyer, Treyarch/Activision
- Fallout: New Vegas – John R. Gonzalez, Obsidian Entertainment/Bethesda Softworks
- Mass Effect 2 – Mac Walters, Drew Karpyshyn, BioWare/Electronic Arts/Microsoft Game Studios
|
Family | Strategy |
Gameplay | Technical Innovation |
Handheld | Use of Audio |
Multiplayer | BAFTA Ones to Watch Award (in association with Dare to Be Digital) |
Original Music - Heavy Rain – Normand Corbeil. Quantic Dream/Sony Computer Entertainment
- Alan Wake – Petri Alanko, Remedy Entertainment/Microsoft Game Studios
- Fable III – Russell Shaw, Lionhead Studios/Microsoft Game Studios
- James Bond 007: Blood Stone – Richard Jacques, Bizarre Creations/Activision
- Mass Effect 2 – Jack Wall, Jimmy Hinson, Sam Hulick, David Kates, BioWare/Electronic Arts/Microsoft Game Studios
- Super Mario Galaxy 2 – Mahito Yokota, Ryo Nagamatsu, Koji Kondo, Nintendo EAD Tokyo/Nintendo
| GAME Award of 2010 |