CD11

In cell biology, CD11 is the α (alpha) component of various integrins, especially ones in which the β (beta) component is CD18 (β2) and mediate leukocyte adhesion.[1] For example,

  • LFA1 (CD11a/CD18) short representation of Lymphocyte Function-associated Antigen 1, also called αLβ2 integrin
  • Mac1 (CD11b/CD18) present on macrophages that is also called Macrophage-1 antigen (CR3) and αMβ2 integrin.
  • CD11c/CD18 also called complement receptor 4 (CR4) and αXβ2 integrin.

References

  1. ^ "CD11 - an overview | ScienceDirect Topics". www.sciencedirect.com. Retrieved 2023-07-07.


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