CHMP2A |
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Identifiers |
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Aliases | CHMP2A, BC-2, BC2, CHMP2, VPS2, VPS2A, charged multivesicular body protein 2A |
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External IDs | OMIM: 610893; MGI: 1916203; HomoloGene: 6382; GeneCards: CHMP2A; OMA:CHMP2A - orthologs |
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Gene location (Human) |
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![Chromosome 19 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/5/54/Ideogram_human_chromosome_19.svg/300px-Ideogram_human_chromosome_19.svg.png) | Chr. | Chromosome 19 (human)[1] |
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| Band | 19q13.43 | Start | 58,551,452 bp[1] |
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End | 58,555,105 bp[1] |
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Gene location (Mouse) |
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![Chromosome 7 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png) | Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7 A1|7 | Start | 12,765,937 bp[2] |
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End | 12,768,734 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - mucosa of transverse colon
- right adrenal gland
- right adrenal cortex
- left adrenal gland
- left adrenal cortex
- oral cavity
- olfactory zone of nasal mucosa
- skin of leg
- apex of heart
- gastric mucosa
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| Top expressed in | - corneal stroma
- saccule
- seminal vesicula
- superior surface of tongue
- arcuate nucleus
- olfactory epithelium
- neural layer of retina
- left colon
- otic vesicle
- skin of external ear
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/3/34/PBB_GE_CHMP2A_202121_s_at_fs.png/250px-PBB_GE_CHMP2A_202121_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein domain specific binding
- phosphatidylcholine binding
- protein binding
| Cellular component | - cytosol
- endosome
- membrane
- late endosome membrane
- membrane coat
- extracellular exosome
- ESCRT III complex
- nuclear envelope
- chromatin
- multivesicular body
| Biological process | - regulation of centrosome duplication
- protein polymerization
- viral budding via host ESCRT complex
- protein heterooligomerization
- nucleus organization
- viral life cycle
- establishment of protein localization
- negative regulation of centriole elongation
- membrane invagination
- multivesicular body assembly
- negative regulation of cell death
- regulation of mitotic spindle assembly
- endosomal transport
- transport
- protein transport
- positive regulation of exosomal secretion
- septum digestion after cytokinesis
- mitotic metaphase plate congression
- protein homooligomerization
- vacuolar transport
- regulation of viral process
- ESCRT III complex disassembly
- nuclear membrane reassembly
- exit from mitosis
- macroautophagy
- endosome transport via multivesicular body sorting pathway
- late endosome to vacuole transport
- midbody abscission
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_026885 NM_001360730 NM_001360731 NM_001360733 |
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RefSeq (protein) | | |
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NP_081161 NP_001347659 NP_001347660 NP_001347662 |
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Location (UCSC) | Chr 19: 58.55 – 58.56 Mb | Chr 7: 12.77 – 12.77 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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