CLASP2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | CLASP2, cytoplasmic linker associated protein 2 |
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External IDs | OMIM: 605853; MGI: 1923749; HomoloGene: 24944; GeneCards: CLASP2; OMA:CLASP2 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3p22.3 | Start | 33,496,245 bp[1] |
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End | 33,718,356 bp[1] |
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Gene location (Mouse) |
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![Chromosome 9 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9|9 F3 | Start | 113,741,473 bp[2] |
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End | 113,919,682 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - corpus callosum
- paraflocculus of cerebellum
- middle frontal gyrus
- Brodmann area 10
- frontal pole
- endothelial cell
- lateral nuclear group of thalamus
- ganglionic eminence
- subthalamic nucleus
- inferior ganglion of vagus nerve
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| Top expressed in | - lateral geniculate nucleus
- inferior colliculus
- medial geniculate nucleus
- pineal gland
- mammillary body
- superior colliculus
- medial dorsal nucleus
- cerebellar vermis
- lobe of cerebellum
- globus pallidus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/0/07/PBB_GE_CLASP2_212306_at_fs.png/250px-PBB_GE_CLASP2_212306_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/PBB_GE_CLASP2_212308_at_fs.png/250px-PBB_GE_CLASP2_212308_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/5/52/PBB_GE_CLASP2_212309_at_fs.png/250px-PBB_GE_CLASP2_212309_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein tyrosine kinase binding
- dystroglycan binding
- microtubule binding
- microtubule plus-end binding
- actin filament binding
- protein binding
- kinetochore binding
| Cellular component | - cytoplasm
- Golgi apparatus
- cell projection
- kinetochore microtubule
- membrane
- focal adhesion
- plasma membrane
- axonal growth cone
- spindle
- microtubule organizing center
- chromosome
- ruffle membrane
- trans-Golgi network
- cell cortex
- cell leading edge
- cortical microtubule plus-end
- cytoplasmic microtubule
- mitotic spindle
- basal cortex
- microtubule
- chromosome, centromeric region
- cytoskeleton
- kinetochore
- cytosol
| Biological process | - vesicle targeting
- regulation of actin cytoskeleton organization
- regulation of axon extension
- Golgi organization
- mitotic spindle organization
- regulation of epithelial to mesenchymal transition
- positive regulation of epithelial cell migration
- exit from mitosis
- cell division
- establishment or maintenance of cell polarity
- positive regulation of extracellular matrix disassembly
- positive regulation of basement membrane assembly involved in embryonic body morphogenesis
- negative regulation of microtubule depolymerization
- microtubule anchoring
- regulation of microtubule-based process
- regulation of microtubule polymerization
- regulation of microtubule polymerization or depolymerization
- negative regulation of wound healing, spreading of epidermal cells
- cell cycle
- positive regulation of exocytosis
- negative regulation of stress fiber assembly
- microtubule organizing center organization
- negative regulation of focal adhesion assembly
- regulation of gastrulation
- microtubule cytoskeleton organization
- microtubule nucleation
- platelet-derived growth factor receptor-beta signaling pathway
- sister chromatid cohesion
- protein localization to plasma membrane
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001207044 NM_015097 NM_001365627 NM_001365628 NM_001365629
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NM_001365630 NM_001365631 NM_001365632 NM_001365633 NM_001365634 NM_001375694 NM_001375697 NM_001375700 NM_001375701 NM_001375703 NM_001375705 NM_001375713 NM_001375715 NM_001375716 NM_001375718 NM_001375720 |
| NM_001081960 NM_001114347 NM_001286599 NM_001286600 NM_001286601
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NM_001286602 NM_001286603 NM_029633 |
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RefSeq (protein) | NP_001193973 NP_055912 NP_001352556 NP_001352557 NP_001352558
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NP_001352559 NP_001352560 NP_001352561 NP_001352562 NP_001352563 NP_001362623 NP_001362626 NP_001362629 NP_001362630 NP_001362632 NP_001362634 NP_001362642 NP_001362644 NP_001362645 NP_001362647 NP_001362649 |
| NP_001075429 NP_001107819 NP_001273528 NP_001273529 NP_001273530
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NP_001273531 NP_001273532 NP_083909 |
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Location (UCSC) | Chr 3: 33.5 – 33.72 Mb | Chr 9: 113.74 – 113.92 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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