CNOT3 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4C0D, 4C0G, 5FU6, 5FU7 |
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Identifiers |
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Aliases | CNOT3, LENG2, NOT3, NOT3H, CCR4-NOT transcription complex subunit 3, IDDSADF |
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External IDs | OMIM: 604910; MGI: 2385261; HomoloGene: 133900; GeneCards: CNOT3; OMA:CNOT3 - orthologs |
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Gene location (Human) |
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![Chromosome 19 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/5/54/Ideogram_human_chromosome_19.svg/300px-Ideogram_human_chromosome_19.svg.png) | Chr. | Chromosome 19 (human)[1] |
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| Band | 19q13.42 | Start | 54,137,749 bp[1] |
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End | 54,155,681 bp[1] |
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Gene location (Mouse) |
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![Chromosome 7 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png) | Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 A1 | Start | 3,645,268 bp[2] |
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End | 3,661,109 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sural nerve
- pituitary gland
- granulocyte
- right uterine tube
- anterior pituitary
- right hemisphere of cerebellum
- ventricular zone
- left lobe of thyroid gland
- right lobe of thyroid gland
- blood
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| Top expressed in | - zygote
- genital tubercle
- tail of embryo
- granulocyte
- ventricular zone
- yolk sac
- neural layer of retina
- lip
- hand
- Rostral migratory stream
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/3/34/PBB_GE_CNOT3_203239_s_at_fs.png/250px-PBB_GE_CNOT3_203239_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/9/90/PBB_GE_CNOT3_211141_s_at_fs.png/250px-PBB_GE_CNOT3_211141_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | | Cellular component | - cytoplasm
- CCR4-NOT complex
- cytosol
- P-body
- nucleus
- CCR4-NOT core complex
| Biological process | - nuclear-transcribed mRNA poly(A) tail shortening
- multicellular organism development
- gene silencing
- negative regulation of translation
- regulation of stem cell population maintenance
- regulation of transcription, DNA-templated
- trophectodermal cell differentiation
- regulation of translation
- transcription, DNA-templated
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
- positive regulation of cold-induced thermogenesis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | ENSG00000088038 ENSG00000277600 ENSG00000277114 ENSG00000274616 ENSG00000275979
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ENSG00000277615 ENSG00000276082 ENSG00000274176 ENSG00000274941 ENSG00000273943 |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 19: 54.14 – 54.16 Mb | Chr 7: 3.65 – 3.66 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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