COMMD4

Protein-coding gene in humans
COMMD4
Identifiers
AliasesCOMMD4, COMM domain containing 4
External IDsOMIM: 616701; MGI: 1913449; HomoloGene: 9865; GeneCards: COMMD4; OMA:COMMD4 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for COMMD4
Genomic location for COMMD4
Band15q24.2Start75,336,020 bp[1]
End75,343,224 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for COMMD4
Genomic location for COMMD4
Band9|9 BStart57,062,319 bp[2]
End57,065,615 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis

  • right testis

  • right adrenal gland

  • right adrenal cortex

  • left adrenal cortex

  • granulocyte

  • mucosa of transverse colon

  • apex of heart

  • stromal cell of endometrium

  • body of stomach
Top expressed in
  • yolk sac

  • blastocyst

  • right kidney

  • ventricular zone

  • neural layer of retina

  • thymus

  • superior frontal gyrus

  • lip

  • otic placode

  • embryo
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • cytoplasm
  • nucleus
Biological process
  • transcription, DNA-templated
  • regulation of transcription, DNA-templated
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

54939

66199

Ensembl

ENSG00000140365

ENSMUSG00000032299

UniProt

Q9H0A8

Q9CQ02

RefSeq (mRNA)
NM_001284377
NM_001284378
NM_001284379
NM_017828
NM_001321844

NM_001321845
NM_001321846
NM_001321847
NM_001321848

NM_025417

RefSeq (protein)
NP_001271306
NP_001271307
NP_001271308
NP_001308773
NP_001308774

NP_001308775
NP_001308776
NP_001308777
NP_060298

NP_079693

Location (UCSC)Chr 15: 75.34 – 75.34 MbChr 9: 57.06 – 57.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

COMM domain-containing protein 4 is a protein that in humans is encoded by the COMMD4 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140365 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032299 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Burstein E, Hoberg JE, Wilkinson AS, Rumble JM, Csomos RA, Komarck CM, Maine GN, Wilkinson JC, Mayo MW, Duckett CS (Jun 2005). "COMMD proteins, a novel family of structural and functional homologs of MURR1". J Biol Chem. 280 (23): 22222–32. doi:10.1074/jbc.M501928200. PMID 15799966.
  6. ^ "Entrez Gene: COMMD4 COMM domain containing 4".

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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