Deslanoside
Chemical compound
- C01AA07 (WHO)
- (3β,5β,12β)-3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
- 17598-65-1 Y
- 28620
- 6806
- DB01078 Y
- 26618 Y
- YGY317RK75
- D01240 Y
- CHEBI:31468 Y
- ChEMBL1614 Y
- DTXSID1022897
InChI
- InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1 Y
- Key:OBATZBGFDSVCJD-LALPQLPRSA-N Y
Deslanoside (trade name Cedilanide in Brazil[1]) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is found in the leaves of Digitalis lanata, the Woolly Foxglove.[2][3]
References
- ^ "Cedilanide". Drugs.com. Archived from the original on 2019-08-15. Retrieved 2018-01-23.
- ^ Bakke OM, Aslaksen A, Lehmann V, Lien E (1981). "Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside". Journal of Cardiovascular Pharmacology. 3 (5): 1015–25. doi:10.1097/00005344-198109000-00012. PMID 6168847.
- ^ Budavari S, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN 0911910123, 2967
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Scilla | |
Kalanchoe |
Digitalis |
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Strophanthus |
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Thevetia |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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