FZD1 |
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Identifiers |
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Aliases | FZD1, frizzled class receptor 1 |
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External IDs | OMIM: 603408; MGI: 1196625; HomoloGene: 20750; GeneCards: FZD1; OMA:FZD1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 7 (human)[1] |
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| Band | 7q21.13 | Start | 91,264,433 bp[1] |
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End | 91,271,326 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5 A1|5 2.61 cM | Start | 4,803,839 bp[2] |
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End | 4,808,035 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - lactiferous duct
- visceral pleura
- tail of epididymis
- tendon of biceps brachii
- Epithelium of choroid plexus
- parietal pleura
- trigeminal ganglion
- superficial temporal artery
- hair follicle
- spinal ganglia
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| Top expressed in | - gastrula
- calvaria
- vas deferens
- belly cord
- habenula
- hair follicle
- aortic valve
- decidua
- ascending aorta
- endocardial cushion
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - PDZ domain binding
- frizzled binding
- signal transducer activity
- Wnt-protein binding
- protein binding
- Wnt-activated receptor activity
- signaling receptor binding
- transmembrane signaling receptor activity
- G protein-coupled receptor activity
| Cellular component | - Wnt signalosome
- membrane
- focal adhesion
- plasma membrane
- cell surface
- integral component of membrane
| Biological process | - G protein-coupled receptor signaling pathway
- positive regulation of protein phosphorylation
- autocrine signaling
- epithelial cell differentiation
- muscular septum morphogenesis
- ventricular septum morphogenesis
- cell-cell signaling
- membranous septum morphogenesis
- outflow tract morphogenesis
- positive regulation of DNA-binding transcription factor activity
- Wnt signaling pathway
- planar cell polarity pathway involved in neural tube closure
- negative regulation of BMP signaling pathway
- positive regulation of transcription, DNA-templated
- multicellular organism development
- cell surface receptor signaling pathway
- canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
- canonical Wnt signaling pathway involved in osteoblast differentiation
- hard palate development
- neuron differentiation
- canonical Wnt signaling pathway
- negative regulation of transcription, DNA-templated
- signal transduction
- Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
- beta-catenin destruction complex disassembly
- Wnt signaling pathway, planar cell polarity pathway
- presynapse assembly
- negative regulation of oxidative stress-induced neuron death
- non-canonical Wnt signaling pathway
- positive regulation of neuron projection development
- negative regulation of canonical Wnt signaling pathway
- regulation of presynapse assembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 7: 91.26 – 91.27 Mb | Chr 5: 4.8 – 4.81 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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