FZD2 |
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Identifiers |
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Aliases | FZD2, Fz2, fz-2, fzE2, hFz2, frizzled class receptor 2, OMOD2 |
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External IDs | OMIM: 600667; MGI: 1888513; HomoloGene: 20377; GeneCards: FZD2; OMA:FZD2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17q21.31 | Start | 44,557,484 bp[1] |
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End | 44,561,262 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 E1 | Start | 102,495,222 bp[2] |
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End | 102,498,884 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - ventricular zone
- embryo
- spinal ganglia
- ganglionic eminence
- stromal cell of endometrium
- trigeminal ganglion
- glomerulus
- metanephric glomerulus
- retinal pigment epithelium
- right coronary artery
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| Top expressed in | - external carotid artery
- internal carotid artery
- ureter
- medullary collecting duct
- mandibular prominence
- vas deferens
- fossa
- maxillary prominence
- condyle
- ascending aorta
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - PDZ domain binding
- signal transducer activity
- protein binding
- transmembrane signaling receptor activity
- G protein-coupled receptor activity
- Wnt-protein binding
- Wnt-activated receptor activity
| Cellular component | - cytoplasm
- clathrin-coated endocytic vesicle membrane
- membrane
- focal adhesion
- plasma membrane
- integral component of membrane
| Biological process | - G protein-coupled receptor signaling pathway
- epithelial cell differentiation
- muscular septum morphogenesis
- ventricular septum morphogenesis
- cell-cell signaling
- membranous septum morphogenesis
- outflow tract morphogenesis
- positive regulation of DNA-binding transcription factor activity
- Wnt signaling pathway
- planar cell polarity pathway involved in neural tube closure
- positive regulation of transcription, DNA-templated
- multicellular organism development
- sensory perception of smell
- cell surface receptor signaling pathway
- inner ear receptor cell development
- hard palate development
- cochlea morphogenesis
- neuron differentiation
- canonical Wnt signaling pathway
- signal transduction
- beta-catenin destruction complex disassembly
- Wnt signaling pathway, calcium modulating pathway
- Wnt signaling pathway, planar cell polarity pathway
- non-canonical Wnt signaling pathway
- positive regulation of G protein-coupled receptor signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 17: 44.56 – 44.56 Mb | Chr 11: 102.5 – 102.5 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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