FZD7 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | FZD7, FzE3, frizzled class receptor 7 |
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External IDs | OMIM: 603410; MGI: 108570; HomoloGene: 20751; GeneCards: FZD7; OMA:FZD7 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q33.1 | Start | 202,033,855 bp[1] |
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End | 202,038,441 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1 C2|1 30.08 cM | Start | 59,521,583 bp[2] |
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End | 59,526,114 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - hair follicle
- germinal epithelium
- urethra
- lactiferous duct
- tibia
- parotid gland
- cerebellar vermis
- parietal pleura
- cardiac muscle tissue of right atrium
- seminal vesicula
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| Top expressed in | - vestibular membrane of cochlear duct
- medullary collecting duct
- renal corpuscle
- ascending aorta
- vestibular sensory epithelium
- Epithelium of choroid plexus
- aortic valve
- saccule
- triceps brachii muscle
- masseter muscle
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - PDZ domain binding
- frizzled binding
- signal transducer activity
- Wnt-protein binding
- protein binding
- transmembrane signaling receptor activity
- phosphatidylinositol-4,5-bisphosphate binding
- G protein-coupled receptor activity
- Wnt-activated receptor activity
| Cellular component | - integral component of membrane
- membrane
- plasma membrane
- recycling endosome membrane
- endosome
- endosome membrane
| Biological process | - negative regulation of cell-substrate adhesion
- cellular response to retinoic acid
- G protein-coupled receptor signaling pathway
- non-canonical Wnt signaling pathway
- regulation of transcription, DNA-templated
- positive regulation of epithelial cell proliferation involved in wound healing
- T cell differentiation in thymus
- non-canonical Wnt signaling pathway via JNK cascade
- negative regulation of ectodermal cell fate specification
- somatic stem cell division
- positive regulation of JNK cascade
- Wnt signaling pathway
- stem cell population maintenance
- positive regulation of transcription, DNA-templated
- multicellular organism development
- cell surface receptor signaling pathway
- skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
- neuron differentiation
- canonical Wnt signaling pathway
- substrate adhesion-dependent cell spreading
- positive regulation of phosphorylation
- signal transduction
- mesenchymal to epithelial transition
- Wnt signaling pathway, planar cell polarity pathway
- negative regulation of cardiac muscle cell differentiation
- regulation of canonical Wnt signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 2: 202.03 – 202.04 Mb | Chr 1: 59.52 – 59.53 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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