FRK |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2D8J, 2DLY |
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Identifiers |
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Aliases | FRK, GTK, PTK5, RAK, Fyn-related kinase, fyn related Src family tyrosine kinase |
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External IDs | OMIM: 606573; MGI: 103265; HomoloGene: 48065; GeneCards: FRK; OMA:FRK - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 6 (human)[1] |
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| Band | 6q22.1 | Start | 115,931,149 bp[1] |
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End | 116,060,891 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 B1 | Start | 34,359,395 bp[2] |
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End | 34,487,274 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - jejunal mucosa
- mucosa of sigmoid colon
- epithelium of nasopharynx
- mucosa of paranasal sinus
- bronchial epithelial cell
- buccal mucosa cell
- palpebral conjunctiva
- parotid gland
- sperm
- corpus epididymis
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| Top expressed in | - seminal vesicula
- jejunum
- duodenum
- renal pelvis
- conjunctival fornix
- large intestine
- colon
- inner renal medulla
- left colon
- Paneth cell
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- nucleotide binding
- protein kinase activity
- kinase activity
- protein binding
- signaling receptor binding
- ATP binding
- non-membrane spanning protein tyrosine kinase activity
- protein tyrosine kinase activity
| Cellular component | - extrinsic component of cytoplasmic side of plasma membrane
- plasma membrane
- intracellular anatomical structure
- extracellular exosome
- extracellular region
- nucleus
- nucleoplasm
- cytoplasm
- azurophil granule lumen
- specific granule lumen
- cytosol
| Biological process | - cell differentiation
- phosphorylation
- transmembrane receptor protein tyrosine kinase signaling pathway
- negative regulation of transcription by RNA polymerase II
- protein phosphorylation
- peptidyl-tyrosine autophosphorylation
- innate immune response
- negative regulation of cell population proliferation
- neutrophil degranulation
- cell migration
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001159544 NM_010237 NM_001358769 |
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RefSeq (protein) | | |
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NP_001153016 NP_034367 NP_001345698 |
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Location (UCSC) | Chr 6: 115.93 – 116.06 Mb | Chr 10: 34.36 – 34.49 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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