Protein-coding gene in the species Homo sapiens
GOLGA8A |
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Identifiers |
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Aliases | GOLGA8A, GM88, golgin A8 family member A, GOLGA8B, CFAP286, FAP286 |
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External IDs | OMIM: 616180; HomoloGene: 121673; GeneCards: GOLGA8A; OMA:GOLGA8A - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 15 (human)[1] |
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| Band | 15q14 | Start | 34,379,068 bp[1] |
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End | 34,437,808 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sural nerve
- right hemisphere of cerebellum
- left lobe of thyroid gland
- right lobe of thyroid gland
- left ovary
- cerebellar vermis
- right ovary
- Brodmann area 23
- sperm
- skin of hip
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| | More reference expression data |
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BioGPS | |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_181077 NM_001368071 NM_001368072 NM_001386893 NM_001386895
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NM_015003 NM_181076 |
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RefSeq (protein) | |
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NP_851422 NP_001355000 NP_001355001 |
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Location (UCSC) | Chr 15: 34.38 – 34.44 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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Golgin A8 family member A is a protein that in humans is encoded by the GOLGA8A gene.[3]
Function
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked, flattened membrane sacs referred to as cisternae. Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins constitute a family of proteins which are localized to the Golgi. This gene encodes a golgin which structurally resembles its family member GOLGA2, suggesting that they may share a similar function. There are many similar copies of this gene on chromosome 15. Alternative splicing results in multiple transcript variants.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000175265 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Golgin A8 family member A". Retrieved 2017-05-31.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.