HKR1

Protein-coding gene in the species Homo sapiens
ZNF875
Identifiers
AliasesZNF875, HKR1, GLI-Kruppel zinc finger family member, zinc finger protein 875, HKR1
External IDsOMIM: 165250; HomoloGene: 65609; GeneCards: ZNF875; OMA:ZNF875 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for ZNF875
Genomic location for ZNF875
Band19q13.12Start37,312,837 bp[1]
End37,369,365 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • pancreatic ductal cell

  • endothelial cell

  • right uterine tube

  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • right hemisphere of cerebellum

  • anterior pituitary

  • apex of heart

  • right adrenal cortex

  • left adrenal cortex
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • multicellular organism development
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

284459

n/a

Ensembl

ENSG00000181666

n/a

UniProt

P10072

n/a

RefSeq (mRNA)
NM_001329761
NM_001329762
NM_001329763
NM_001329764
NM_001329765

NM_001329766
NM_001329767
NM_001329768
NM_001329769
NM_001329770
NM_001329771
NM_001329772
NM_001329773
NM_001329774
NM_001329775
NM_001329776
NM_001329777
NM_001329778
NM_001329779
NM_181786
NM_001353803
NM_001353804

n/a

RefSeq (protein)
NP_001316690
NP_001316691
NP_001316692
NP_001316693
NP_001316694

NP_001316695
NP_001316696
NP_001316697
NP_001316698
NP_001316699
NP_001316700
NP_001316701
NP_001316702
NP_001316703
NP_001316704
NP_001316705
NP_001316706
NP_001316707
NP_001316708
NP_861451
NP_001340732
NP_001340733

n/a

Location (UCSC)Chr 19: 37.31 – 37.37 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Krueppel-related zinc finger protein 1 is a protein that in humans is encoded by the HKR1 gene.[3][4][5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181666 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Ruppert JM, Kinzler KW, Wong AJ, Bigner SH, Kao FT, Law ML, Seuanez HN, O'Brien SJ, Vogelstein B (Feb 1989). "The GLI-Kruppel family of human genes". Mol Cell Biol. 8 (8): 3104–13. doi:10.1128/mcb.8.8.3104. PMC 363537. PMID 2850480.
  4. ^ Oguri T, Katoh O, Takahashi T, Isobe T, Kuramoto K, Hirata S, Yamakido M, Watanabe H (Jan 1999). "The Kruppel-type zinc finger family gene, HKR1, is induced in lung cancer by exposure to platinum drugs". Gene. 222 (1): 61–7. doi:10.1016/S0378-1119(98)00464-8. PMID 9813242.
  5. ^ "Entrez Gene: HKR1 GLI-Kruppel family member HKR1".

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Matsumoto N, Fujimoto M, Kato R, Niikawa N (1997). "Assignment of the human GLI2 gene to 2q14 by fluorescence in situ hybridization". Genomics. 36 (1): 220–1. doi:10.1006/geno.1996.0454. PMID 8812445.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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