HMG20A

Protein-coding gene in the species Homo sapiens
HMG20A
Identifiers
AliasesHMG20A, HMGX1, HMGXB1, high mobility group 20A
External IDsOMIM: 605534; MGI: 1914117; HomoloGene: 32399; GeneCards: HMG20A; OMA:HMG20A - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for HMG20A
Genomic location for HMG20A
Band15q24.3Start77,420,412 bp[1]
End77,485,607 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for HMG20A
Genomic location for HMG20A
Band9|9 BStart56,325,893 bp[2]
End56,404,220 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • epithelium of colon

  • oocyte

  • secondary oocyte

  • embryo

  • ganglionic eminence

  • tibia

  • prefrontal cortex

  • vastus lateralis muscle

  • tonsil

  • rectum
Top expressed in
  • nucleus of stria terminalis

  • zygote

  • secondary oocyte

  • vestibular sensory epithelium

  • medial dorsal nucleus

  • subiculum

  • superior colliculus

  • medial geniculate nucleus

  • olfactory tubercle

  • paraventricular nucleus of hypothalamus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • protein heterodimerization activity
  • DNA binding
  • protein binding
  • identical protein binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • nucleus
Biological process
  • regulation of transcription, DNA-templated
  • negative regulation of transcription by RNA polymerase II
  • negative regulation of neuron differentiation
  • transcription, DNA-templated
  • negative regulation of protein sumoylation
  • chromatin organization
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10363

66867

Ensembl

ENSG00000140382

ENSMUSG00000032329

UniProt

Q9NP66

Q9DC33

RefSeq (mRNA)

NM_001304504
NM_001304505
NM_018200

NM_025812

RefSeq (protein)

NP_001291433
NP_001291434
NP_060670

NP_080088

Location (UCSC)Chr 15: 77.42 – 77.49 MbChr 9: 56.33 – 56.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

High mobility group protein 20A is a protein that in humans is encoded by the HMG20A gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140382 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032329 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sumoy L, Carim L, Escarceller M, Nadal M, Gratacòs M, Pujana MA, Estivill X, Peral B (Jun 2000). "HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression". Cytogenetics and Cell Genetics. 88 (1–2): 62–7. doi:10.1159/000015486. PMID 10773667. S2CID 22921110.
  6. ^ "Entrez Gene: HMG20A high-mobility group 20A".

Further reading

  • Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (July 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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