Loganate O-methyltransferase
loganate O-methyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.1.1.50 | ||||||||
CAS no. | 39391-10-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a loganate O-methyltransferase (EC 2.1.1.50) is an enzyme that catalyzes the chemical reaction.
- S-adenosyl-L-methionine + loganic acid S-adenosyl-L-homocysteine + loganin
Thus, the two substrates of this enzyme are S-adenosyl methionine and loganic acid (also called loganate), whereas its two products are S-adenosylhomocysteine and loganin.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon-group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:loganate 11-O-methyltransferase. Other names in common use include loganate methyltransferase and S-adenosyl-L-methionine:loganic acid methyltransferase. This enzyme participates in terpene indole and ipecac alkaloid biosynthesis.
References
- Madyastha KM, Guarnaccia R, Baxter C, Coscia CJ (1973). "S-Adenosyl-L-methionine: loganic acid methyltransferase. A carboxyl-alkylating enzyme from Vinca rosea". J. Biol. Chem. 248 (7): 2497–501. PMID 4698228.
- v
- t
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Transferase: one carbon transferases (EC 2.1)
N- | |
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O- | |
Homocysteine | |
Other |
Formyl- and Related
Hydroxymethyltransferase | |
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Formyltransferase | |
Other |
and Carbamoyl
Carboxy | |
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Carbamoyl |
- Arginine:glycine amidinotransferase