MBTPS1 |
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Identifiers |
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Aliases | MBTPS1, membrane-bound transcription factor peptidase, site 1, PCSK8, S1P, SKI-1, membrane bound transcription factor peptidase, site 1, SEDKF |
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External IDs | OMIM: 603355; MGI: 1927235; HomoloGene: 2808; GeneCards: MBTPS1; OMA:MBTPS1 - orthologs |
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Gene location (Human) |
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![Chromosome 16 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/300px-Ideogram_human_chromosome_16.svg.png) | Chr. | Chromosome 16 (human)[1] |
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| Band | 16q23.3-q24.1 | Start | 84,053,761 bp[1] |
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End | 84,116,942 bp[1] |
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Gene location (Mouse) |
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![Chromosome 8 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Ideogram_house_mouse_chromosome_8.svg/260px-Ideogram_house_mouse_chromosome_8.svg.png) | Chr. | Chromosome 8 (mouse)[2] |
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| Band | 8|8 E1 | Start | 120,234,895 bp[2] |
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End | 120,285,474 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - stromal cell of endometrium
- pituitary gland
- left ovary
- anterior pituitary
- cerebellar hemisphere
- right hemisphere of cerebellum
- right ovary
- islet of Langerhans
- right uterine tube
- right lobe of thyroid gland
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| Top expressed in | - saccule
- molar
- Gonadal ridge
- otic vesicle
- otic placode
- tail of embryo
- efferent ductule
- calvaria
- vas deferens
- medullary collecting duct
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - endopeptidase activity
- peptidase activity
- serine-type peptidase activity
- hydrolase activity
- serine-type endopeptidase activity
- metalloendopeptidase activity
| Cellular component | - integral component of membrane
- Golgi apparatus
- endoplasmic reticulum lumen
- membrane
- Golgi membrane
- endoplasmic reticulum
- Golgi stack
- endoplasmic reticulum membrane
| Biological process | - steroid metabolic process
- lipid metabolism
- cholesterol metabolic process
- response to endoplasmic reticulum stress
- proteolysis
- ATF6-mediated unfolded protein response
- membrane protein intracellular domain proteolysis
- lysosome organization
- endoplasmic reticulum unfolded protein response
- post-translational protein modification
- regulation of cholesterol biosynthetic process
- protein import into nucleus
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 16: 84.05 – 84.12 Mb | Chr 8: 120.23 – 120.29 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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