MYOCD |
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Identifiers |
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Aliases | MYOCD, MYCD, myocardin, MGBL |
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External IDs | OMIM: 606127; MGI: 2137495; HomoloGene: 17043; GeneCards: MYOCD; OMA:MYOCD - orthologs |
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Gene location (Human) |
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![Chromosome 17 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 (human)[1] |
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| Band | 17p12 | Start | 12,665,890 bp[1] |
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End | 12,768,949 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B3 | Start | 65,067,387 bp[2] |
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End | 65,160,815 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - tail of epididymis
- saphenous vein
- cardiac muscle tissue of right atrium
- right ventricle
- nipple
- urethra
- right coronary artery
- superficial temporal artery
- ascending aorta
- smooth muscle tissue
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| Top expressed in | - ascending aorta
- aortic valve
- tunica media of zone of aorta
- belly cord
- myocardium of ventricle
- interventricular septum
- atrium
- vas deferens
- migratory enteric neural crest cell
- cumulus cell
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/PBB_GE_MYOCD_gnf1h03126_at_fs.png/250px-PBB_GE_MYOCD_gnf1h03126_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - transcription coactivator activity
- R-SMAD binding
- DNA-binding transcription activator activity, RNA polymerase II-specific
- transcription factor binding
- histone deacetylase binding
- core promoter sequence-specific DNA binding
- protein binding
- histone acetyltransferase binding
- cis-regulatory region sequence-specific DNA binding
- RNA polymerase II-specific DNA-binding transcription factor binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
| Cellular component | | Biological process | - cellular component maintenance
- positive regulation of transforming growth factor beta receptor signaling pathway
- response to hypoxia
- regulation of transcription, DNA-templated
- negative regulation of cyclin-dependent protein serine/threonine kinase activity
- urinary bladder development
- regulation of transcription by RNA polymerase II
- vascular associated smooth muscle cell differentiation
- cardiac ventricle development
- regulation of cell growth by extracellular stimulus
- positive regulation of DNA-binding transcription factor activity
- negative regulation of transcription by RNA polymerase II
- smooth muscle cell differentiation
- transcription, DNA-templated
- regulation of phenotypic switching
- vasculogenesis
- positive regulation of transcription, DNA-templated
- uterus development
- negative regulation of skeletal muscle cell differentiation
- negative regulation of cardiac muscle cell apoptotic process
- heart development
- muscle cell differentiation
- negative regulation of amyloid-beta clearance
- positive regulation of smooth muscle cell differentiation
- regulation of myoblast differentiation
- regulation of histone acetylation
- positive regulation of cell population proliferation
- negative regulation of myotube differentiation
- positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
- positive regulation of cardiac vascular smooth muscle cell differentiation
- positive regulation of cardiac muscle cell differentiation
- ventricular cardiac muscle cell differentiation
- positive regulation of DNA binding
- lung alveolus development
- digestive tract development
- positive regulation of smooth muscle contraction
- cardiocyte differentiation
- ductus arteriosus closure
- positive regulation of transcription by RNA polymerase II
- negative regulation of cell population proliferation
- regulation of smooth muscle cell differentiation
- transcription by RNA polymerase II
- cardiac muscle cell differentiation
- positive regulation of gene expression
- negative regulation of vascular associated smooth muscle cell proliferation
- negative regulation of vascular associated smooth muscle cell migration
- negative regulation of platelet-derived growth factor receptor-beta signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001146312 NM_001146313 NM_153604 NM_001378306 |
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RefSeq (protein) | |
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NP_001139784 NP_705832 NP_001365235 |
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Location (UCSC) | Chr 17: 12.67 – 12.77 Mb | Chr 11: 65.07 – 65.16 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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