NECAB2 |
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Identifiers |
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Aliases | NECAB2, EFCBP2, N-terminal EF-hand calcium binding protein 2, stip-2 |
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External IDs | OMIM: 618130; MGI: 2152211; HomoloGene: 62200; GeneCards: NECAB2; OMA:NECAB2 - orthologs |
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Gene location (Human) |
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![Chromosome 16 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/300px-Ideogram_human_chromosome_16.svg.png) | Chr. | Chromosome 16 (human)[1] |
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| Band | 16q23.3 | Start | 83,968,244 bp[1] |
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End | 84,002,776 bp[1] |
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Gene location (Mouse) |
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![Chromosome 8 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Ideogram_house_mouse_chromosome_8.svg/260px-Ideogram_house_mouse_chromosome_8.svg.png) | Chr. | Chromosome 8 (mouse)[2] |
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| Band | 8|8 E1 | Start | 120,173,458 bp[2] |
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End | 120,199,379 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - nucleus accumbens
- caudate nucleus
- amygdala
- putamen
- cingulate gyrus
- anterior cingulate cortex
- right frontal lobe
- Brodmann area 9
- hypothalamus
- prefrontal cortex
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| Top expressed in | - habenula
- olfactory tubercle
- lateral septal nucleus
- dentate gyrus of hippocampal formation granule cell
- medial geniculate nucleus
- anterior amygdaloid area
- medial dorsal nucleus
- subiculum
- nucleus accumbens
- globus pallidus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/9/93/PBB_GE_EFCBP2_215005_at_fs.png/250px-PBB_GE_EFCBP2_215005_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - metal ion binding
- protein binding
- calcium ion binding
- A2A adenosine receptor binding
- type 5 metabotropic glutamate receptor binding
- identical protein binding
| Cellular component | - cytoplasm
- plasma membrane
- membrane
- axon
- dendrite
- cell projection
| Biological process | - positive regulation of adenosine receptor signaling pathway
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of glutamate receptor signaling pathway
- negative regulation of G protein-coupled receptor internalization
- positive regulation of protein localization to membrane
- regulation of amyloid precursor protein biosynthetic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_019065 NM_001329748 NM_001329749 |
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RefSeq (protein) | |
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NP_001316677 NP_001316678 NP_061938 |
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Location (UCSC) | Chr 16: 83.97 – 84 Mb | Chr 8: 120.17 – 120.2 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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