NOB1

Protein-coding gene in the species Homo sapiens
NOB1
Identifiers
AliasesNOB1, ART-4, MST158, NOB1P, PSMD8BP1, MSTP158, NIN1/PSMD8 binding protein 1 homolog, NIN1 (RPN12) binding protein 1 homolog
External IDsOMIM: 613586; MGI: 1914869; HomoloGene: 31924; GeneCards: NOB1; OMA:NOB1 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for NOB1
Genomic location for NOB1
Band16q22.1Start69,741,871 bp[1]
End69,754,926 bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for NOB1
Genomic location for NOB1
Band8|8 D3Start108,139,118 bp[2]
End108,151,683 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • right adrenal gland

  • right adrenal cortex

  • left adrenal gland

  • left adrenal cortex

  • left ovary

  • stromal cell of endometrium

  • uterine tube

  • right ovary

  • mucosa of esophagus
Top expressed in
  • hand

  • epiblast

  • morula

  • embryo

  • embryo

  • primitive streak

  • otolith organ

  • utricle

  • ventricular zone

  • foot
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • metal ion binding
  • endoribonuclease activity
Cellular component
  • preribosome, small subunit precursor
  • nucleus
  • cytosol
  • nucleoplasm
Biological process
  • maturation of SSU-rRNA
  • visual perception
  • RNA phosphodiester bond hydrolysis, endonucleolytic
  • rRNA processing
  • cleavage involved in rRNA processing
  • ribosomal small subunit biogenesis
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

28987

67619

Ensembl

ENSG00000141101

ENSMUSG00000003848

UniProt

Q9ULX3

Q8BW10

RefSeq (mRNA)

NM_014062

NM_026277

RefSeq (protein)

NP_054781

NP_080553

Location (UCSC)Chr 16: 69.74 – 69.75 MbChr 8: 108.14 – 108.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141101 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003848 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhang Y, Ni J, Zhou G, Yuan J, Ren W, Shan Y, Tang W, Yu L, Zhao S (Sep 2005). "Cloning, expression and characterization of the human NOB1 gene". Mol Biol Rep. 32 (3): 185–9. doi:10.1007/s11033-005-3141-7. PMID 16172919. S2CID 12892523.
  6. ^ "Entrez Gene: NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)".

Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Fatica A, Oeffinger M, Dlakić M, Tollervey D (2003). "Nob1p is required for cleavage of the 3' end of 18S rRNA". Mol. Cell. Biol. 23 (5): 1798–807. doi:10.1128/MCB.23.5.1798-1807.2003. PMC 151717. PMID 12588997.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Daniele A, Altruda F, Ferrone M, et al. (1992). "Cloning and expression of a new human polypeptide which regulates protein phosphorylation in Escherichia coli". Mol. Cell. Biochem. 107 (2): 87–94. doi:10.1007/bf00225511. PMID 1791827. S2CID 25617287.
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  • 2con: Solution Structure of RSGI RUH-035, a Zn-ribbon module in Mouse cDNA
    2con: Solution Structure of RSGI RUH-035, a Zn-ribbon module in Mouse cDNA


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