Protein-coding gene in the species Homo sapiens
| OR2AG2 |
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| Identifiers |
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| Aliases | OR2AG2, OR11-76, OR2AG2P, olfactory receptor family 2 subfamily AG member 2 |
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| External IDs | MGI: 3030535; HomoloGene: 12558; GeneCards: OR2AG2; OMA:OR2AG2 - orthologs |
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| Gene location (Human) |
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 | | Chr. | Chromosome 11 (human)[1] |
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| | Band | 11p15.4 | Start | 6,765,626 bp[1] |
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| End | 6,771,976 bp[1] |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 7 (mouse)[2] |
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| | Band | 7|7 E3 | Start | 106,413,336 bp[2] |
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| End | 106,420,679 bp[2] |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - testicle
- gonad
- prefrontal cortex
- duodenum
- primary visual cortex
- urinary bladder
- appendix
- muscle tissue
- olfactory zone of nasal mucosa
- islet of Langerhans
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| | Top expressed in | - spermatid
- olfactory epithelium
- zygote
- lumbar subsegment of spinal cord
- seminiferous tubule
- lumbar spinal ganglion
- oocyte
- gastrula
- primary oocyte
- secondary oocyte
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| | More reference expression data |
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| BioGPS | |
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| Gene ontology |
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| Molecular function | - G protein-coupled receptor activity
- olfactory receptor activity
- signal transducer activity
| | Cellular component | - integral component of membrane
- plasma membrane
- membrane
| | Biological process | - sensory perception of smell
- signal transduction
- response to stimulus
- detection of chemical stimulus involved in sensory perception of smell
- G protein-coupled receptor signaling pathway
| | Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 11: 6.77 – 6.77 Mb | Chr 7: 106.41 – 106.42 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
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Olfactory receptor family 2 subfamily AG member 2 is a protein that in humans is encoded by the OR2AG2 gene.[5]
Function
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000188124 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036744 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Olfactory receptor family 2 subfamily AG member 2". Retrieved 2018-02-21.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
