PARP16

Protein-coding gene in the species Homo sapiens
PARP16
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4F0D

Identifiers
AliasesPARP16, ARTD15, C15orf30, pART15, poly(ADP-ribose) polymerase family member 16
External IDsMGI: 2446133; HomoloGene: 9878; GeneCards: PARP16; OMA:PARP16 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for PARP16
Genomic location for PARP16
Band15q22.31Start65,234,460 bp[1]
End65,300,618 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for PARP16
Genomic location for PARP16
Band9|9 CStart65,102,635 bp[2]
End65,146,506 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • gonad

  • testicle

  • Achilles tendon

  • canal of the cervix

  • ganglionic eminence

  • left ovary

  • right ovary

  • granulocyte

  • right lobe of liver
Top expressed in
  • saccule

  • otic vesicle

  • lacrimal gland

  • liver

  • right kidney

  • Ileal epithelium

  • islet of Langerhans

  • granulocyte

  • proximal tubule

  • brown adipose tissue
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • transferase activity
  • kinase binding
  • protein serine/threonine kinase activator activity
  • protein binding
  • glycosyltransferase activity
  • NAD+ ADP-ribosyltransferase activity
  • protein ADP-ribosylase activity
Cellular component
  • integral component of membrane
  • nuclear envelope
  • endoplasmic reticulum
  • endoplasmic reticulum membrane
  • membrane
  • endoplasmic reticulum tubular network
  • cytosol
Biological process
  • endoplasmic reticulum unfolded protein response
  • protein auto-ADP-ribosylation
  • response to unfolded protein
  • protein ADP-ribosylation
  • negative regulation of cell death
  • positive regulation of protein serine/threonine kinase activity
  • NAD biosynthesis via nicotinamide riboside salvage pathway
  • cellular response to leukemia inhibitory factor
  • IRE1-mediated unfolded protein response
  • protein mono-ADP-ribosylation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

54956

214424

Ensembl

ENSG00000138617

ENSMUSG00000032392

UniProt

Q8N5Y8

Q7TMM8

RefSeq (mRNA)

NM_017851
NM_001316943
NM_001316944

NM_177460

RefSeq (protein)

NP_001303872
NP_001303873
NP_060321

NP_803411

Location (UCSC)Chr 15: 65.23 – 65.3 MbChr 9: 65.1 – 65.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Poly (ADP-ribose) polymerase family, member 16 is a protein in humans that is encoded by the PARP16 gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138617 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032392 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Poly (ADP-ribose) polymerase family, member 16". Retrieved 2013-04-03.
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Protein mono-ADP-ribosyltransferase PARP16


Further reading


  • v
  • t
  • e