PHF12 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2L9S, 2LKM |
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Identifiers |
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Aliases | PHF12, PF1, PHD finger protein 12 |
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External IDs | MGI: 1924057; HomoloGene: 10841; GeneCards: PHF12; OMA:PHF12 - orthologs |
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Gene location (Human) |
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![Chromosome 17 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 (human)[1] |
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| Band | 17q11.2 | Start | 28,905,250 bp[1] |
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End | 28,951,771 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B5 | Start | 77,873,580 bp[2] |
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End | 77,921,365 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sural nerve
- granulocyte
- bone marrow cells
- stromal cell of endometrium
- spleen
- right lung
- blood
- appendix
- gastric mucosa
- ganglionic eminence
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| Top expressed in | - genital tubercle
- tail of embryo
- neural layer of retina
- granulocyte
- ventricular zone
- zygote
- superior frontal gyrus
- dentate gyrus of hippocampal formation granule cell
- thymus
- secondary oocyte
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/5/5f/PBB_GE_PHF12_gnf1h07489_at_fs.png/250px-PBB_GE_PHF12_gnf1h07489_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - transcription corepressor binding
- histone binding
- transcription corepressor activity
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- chromatin binding
- protein binding
- phosphatidylinositol binding
- metal ion binding
| Cellular component | - transcription repressor complex
- Sin3 complex
- nucleus
- nucleoplasm
- Sin3-type complex
| Biological process | - negative regulation of transcription, DNA-templated
- regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- transcription, DNA-templated
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001033561 NM_001290131 NM_020889 |
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RefSeq (protein) | |
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NP_001028733 NP_001277060 NP_065940 |
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Location (UCSC) | Chr 17: 28.91 – 28.95 Mb | Chr 11: 77.87 – 77.92 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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