PJA2 |
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Identifiers |
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Aliases | PJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 2 |
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External IDs | MGI: 2159342; HomoloGene: 32233; GeneCards: PJA2; OMA:PJA2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 5 (human)[1] |
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| Band | 5q21.3 | Start | 109,334,713 bp[1] |
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End | 109,409,974 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 17 (mouse)[2] |
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| Band | 17|17 E1.1 | Start | 64,588,000 bp[2] |
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End | 64,638,911 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - tail of epididymis
- postcentral gyrus
- frontal pole
- Achilles tendon
- Brodmann area 46
- prefrontal cortex
- orbitofrontal cortex
- pons
- caput epididymis
- superior vestibular nucleus
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| Top expressed in | - interventricular septum
- medial dorsal nucleus
- dorsal striatum
- temporal lobe
- olfactory tubercle
- globus pallidus
- inferior colliculus
- facial motor nucleus
- Region I of hippocampus proper
- nucleus accumbens
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - protein kinase A regulatory subunit binding
- ubiquitin-protein transferase activity
- protein kinase A catalytic subunit binding
- ubiquitin protein ligase activity
- metal ion binding
- transferase activity
- protein binding
| Cellular component | - Golgi membrane
- postsynaptic density
- membrane
- endoplasmic reticulum
- synapse
- plasma membrane
- cytoplasm
- cell junction
- postsynaptic membrane
- Golgi apparatus
- intermediate filament cytoskeleton
- endoplasmic reticulum membrane
| Biological process | - hippo signaling
- regulation of protein kinase A signaling
- long-term memory
- protein ubiquitination
- inflammatory response
- positive regulation of toll-like receptor 2 signaling pathway
- regulation of macrophage activation
- innate immune response
- positive regulation of JNK cascade
- positive regulation of p38MAPK cascade
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 5: 109.33 – 109.41 Mb | Chr 17: 64.59 – 64.64 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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