RASL11B

Protein-coding gene in the species Homo sapiens
RASL11B
Identifiers
AliasesRASL11B, RAS like family 11 member B
External IDsOMIM: 612404; MGI: 1916189; HomoloGene: 74291; GeneCards: RASL11B; OMA:RASL11B - orthologs
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for RASL11B
Genomic location for RASL11B
Band4q12Start52,862,317 bp[1]
End52,866,835 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for RASL11B
Genomic location for RASL11B
Band5|5 C3.3Start74,355,947 bp[2]
End74,360,142 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right ovary

  • left ovary

  • spleen

  • cerebellar hemisphere

  • right hemisphere of cerebellum

  • testicle

  • right coronary artery

  • ganglionic eminence

  • stromal cell of endometrium

  • prefrontal cortex
Top expressed in
  • transitional epithelium of urinary bladder

  • vas deferens

  • molar

  • endocardial cushion

  • lens

  • epithelium of lens

  • semi-lunar valve

  • medullary collecting duct

  • ascending aorta

  • Region I of hippocampus proper
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • nucleotide binding
  • transforming growth factor beta receptor binding
  • GTP binding
  • GTPase activity
Cellular component
  • membrane
Biological process
  • negative regulation of transforming growth factor beta receptor signaling pathway
  • signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

65997

68939

Ensembl

ENSG00000128045

ENSMUSG00000049907

UniProt

Q9BPW5

Q922H7

RefSeq (mRNA)

NM_023940

NM_026878

RefSeq (protein)

NP_076429

NP_081154

Location (UCSC)Chr 4: 52.86 – 52.87 MbChr 5: 74.36 – 74.36 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ras-like protein family member 11B is a protein that in humans is encoded by the RASL11B gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128045 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049907 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: RASL11B RAS-like, family 11, member B".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Louro R, Nakaya HI, Paquola AC, et al. (2004). "RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors". Biochem. Biophys. Res. Commun. 316 (3): 618–27. doi:10.1016/j.bbrc.2004.02.091. PMID 15033445.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Stolle K, Schnoor M, Fuellen G, et al. (2007). "Cloning, genomic organization, and tissue-specific expression of the RASL11B gene". Biochim. Biophys. Acta. 1769 (7–8): 514–24. doi:10.1016/j.bbaexp.2007.05.005. PMID 17628721.
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