Ring finger protein 157

Protein-coding gene in the species Homo sapiens
RNF157
Identifiers
AliasesRNF157, ring finger protein 157
External IDsMGI: 2442484; HomoloGene: 28235; GeneCards: RNF157; OMA:RNF157 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for RNF157
Genomic location for RNF157
Band17q25.1Start76,142,465 bp[1]
End76,240,493 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for RNF157
Genomic location for RNF157
Band11|11 E2Start116,227,179 bp[2]
End116,303,858 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • lateral nuclear group of thalamus

  • right frontal lobe

  • cingulate gyrus

  • anterior cingulate cortex

  • dorsolateral prefrontal cortex

  • Brodmann area 9

  • Pars compacta

  • prefrontal cortex

  • pars reticulata

  • gastrocnemius muscle
Top expressed in
  • motor neuron

  • facial motor nucleus

  • trigeminal ganglion

  • substantia nigra

  • dentate gyrus of hippocampal formation granule cell

  • Region I of hippocampus proper

  • superior frontal gyrus

  • visual cortex

  • primary visual cortex

  • retinal pigment epithelium
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • metal ion binding
  • transferase activity
  • ubiquitin protein ligase activity
Cellular component
  • cytoplasm
  • cell body
Biological process
  • protein ubiquitination
  • negative regulation of apoptotic process
  • protein autoubiquitination
  • positive regulation of dendrite extension
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

114804

217340

Ensembl

ENSG00000141576

ENSMUSG00000052949

UniProt

Q96PX1

Q3TEL6

RefSeq (mRNA)

NM_052916
NM_001330501

NM_027258

RefSeq (protein)

NP_001317430
NP_443148

n/a

Location (UCSC)Chr 17: 76.14 – 76.24 MbChr 11: 116.23 – 116.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ring finger protein 157 is a protein that in humans is encoded by the RNF157 gene. [5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141576 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052949 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Ring finger protein 157". Retrieved 2018-06-29.

Further reading

  • Talmud PJ, et al. (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
  • Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
  • Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
  • Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A (December 2010). "Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study". Mutat. Res. 694 (1–2): 13–9. doi:10.1016/j.mrfmmm.2010.08.006. PMID 20800603.


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