SCAMP5

Protein-coding gene in the species Homo sapiens
SCAMP5
Identifiers
AliasesSCAMP5, secretory carrier membrane protein 5
External IDsOMIM: 613766; MGI: 1928948; HomoloGene: 56880; GeneCards: SCAMP5; OMA:SCAMP5 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for SCAMP5
Genomic location for SCAMP5
Band15q24.2Start74,957,219 bp[1]
End75,021,495 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for SCAMP5
Genomic location for SCAMP5
Band9|9 BStart57,348,610 bp[2]
End57,375,343 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right hemisphere of cerebellum

  • right frontal lobe

  • prefrontal cortex

  • anterior cingulate cortex

  • Brodmann area 9

  • Brodmann area 10

  • nucleus accumbens

  • amygdala

  • islet of Langerhans

  • caudate nucleus
Top expressed in
  • neural layer of retina

  • dentate gyrus of hippocampal formation granule cell

  • primary visual cortex

  • superior frontal gyrus

  • cerebellar cortex

  • central gray substance of midbrain

  • subiculum

  • nucleus of stria terminalis

  • hippocampus proper

  • prefrontal cortex
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
  • protein-containing complex binding
Cellular component
  • integral component of membrane
  • cell junction
  • Golgi membrane
  • recycling endosome membrane
  • plasma membrane
  • endosome
  • Golgi apparatus
  • SNARE complex
  • synapse
  • trans-Golgi network membrane
  • synaptic vesicle membrane
  • membrane
  • cytoplasmic vesicle
Biological process
  • protein transport
  • negative regulation of endocytosis
  • response to endoplasmic reticulum stress
  • exocytosis
  • positive regulation of calcium ion-dependent exocytosis
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

192683

56807

Ensembl

ENSG00000198794

ENSMUSG00000040722

UniProt

Q8TAC9

Q9JKD3

RefSeq (mRNA)

NM_001178111
NM_001178112
NM_138967

NM_001301634
NM_001301635
NM_020270

RefSeq (protein)
NP_001171582
NP_001171583
NP_620417
NP_001171582.1
NP_001171583.1

NP_620417.1

NP_001288563
NP_001288564
NP_064666

Location (UCSC)Chr 15: 74.96 – 75.02 MbChr 9: 57.35 – 57.38 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Secretory carrier-associated membrane protein 5 is a protein that in humans is encoded by the SCAMP5 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198794 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040722 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ "Entrez Gene: SCAMP5 secretory carrier membrane protein 5".

Further reading

  • Fernández-Chacón R, Südhof TC (November 2000). "Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions" (PDF). The Journal of Neuroscience. 20 (21): 7941–50. doi:10.1523/jneurosci.20-21-07941.2000. PMC 6772721. PMID 11050114.
  • Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Lin PJ, Williams WP, Luu Y, Molday RS, Orlowski J, Numata M (May 2005). "Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7". Journal of Cell Science. 118 (Pt 9): 1885–97. doi:10.1242/jcs.02315. PMID 15840657.
  • Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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