SFRS16

Protein-coding gene in the species Homo sapiens
CLASRP
Identifiers
AliasesCLASRP, CLASP, SFRS16, SWAP2, CLK4 associating serine/arginine rich protein
External IDsOMIM: 618532; MGI: 1855695; GeneCards: CLASRP; OMA:CLASRP - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for CLASRP
Genomic location for CLASRP
Band19q13.32Start45,039,045 bp[1]
End45,070,956 bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for CLASRP
Genomic location for CLASRP
Band7|7 A3Start19,581,035 bp[2]
End19,604,486 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • anterior pituitary

  • sural nerve

  • left ovary

  • right ovary

  • right lobe of thyroid gland

  • C1 segment

  • right hemisphere of cerebellum

  • left lobe of thyroid gland

  • granulocyte

  • body of uterus
Top expressed in
  • neural layer of retina

  • superior frontal gyrus

  • cerebellar cortex

  • granulocyte

  • internal carotid artery

  • external carotid artery

  • dorsal tegmental nucleus

  • ventricular zone

  • primary visual cortex

  • seminiferous tubule
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • nucleus
  • nucleoplasm
Biological process
  • RNA splicing
  • mRNA processing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

11129

53609

Ensembl

ENSG00000104859

ENSMUSG00000061028

UniProt

Q8N2M8

Q8CFC7

RefSeq (mRNA)

NM_001278439
NM_007056

NM_016680

RefSeq (protein)

NP_001265368
NP_008987
NP_008987.2

NP_057889

Location (UCSC)Chr 19: 45.04 – 45.07 MbChr 7: 19.58 – 19.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Splicing factor, arginine/serine-rich 16 is a protein that in humans is encoded by the SFRS16 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000104859 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061028 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Katsu R, Onogi H, Wada K, Kawaguchi Y, Hagiwara M (Nov 2002). "Novel SR-rich-related protein clasp specifically interacts with inactivated Clk4 and induces the exon EB inclusion of Clk". J Biol Chem. 277 (46): 44220–8. doi:10.1074/jbc.M206504200. PMID 12169693.
  6. ^ "Entrez Gene: SFRS16 splicing factor, arginine/serine-rich 16".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • de Graaf K, Hekerman P, Spelten O, et al. (2004). "Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors". J. Biol. Chem. 279 (6): 4612–24. doi:10.1074/jbc.M310794200. PMID 14623875.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.


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