STOML1

Protein-coding gene in the species Homo sapiens
STOML1
Identifiers
AliasesSTOML1, SLP-1, STORP, hUNC-24, stomatin like 1
External IDsOMIM: 608326; MGI: 1916356; HomoloGene: 31265; GeneCards: STOML1; OMA:STOML1 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for STOML1
Genomic location for STOML1
Band15q24.1Start73,978,926 bp[1]
End73,994,622 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for STOML1
Genomic location for STOML1
Band9|9 BStart58,160,447 bp[2]
End58,169,803 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • pancreatic ductal cell

  • endothelial cell

  • tendon of biceps brachii

  • frontal pole

  • prefrontal cortex

  • superior vestibular nucleus

  • Brodmann area 9

  • Brodmann area 23

  • right frontal lobe

  • cingulate gyrus
Top expressed in
  • dentate gyrus of hippocampal formation granule cell

  • visual cortex

  • primary visual cortex

  • spinal ganglia

  • neural layer of retina

  • lumbar spinal ganglion

  • superior frontal gyrus

  • neural tube

  • otolith organ

  • utricle
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein binding
  • molecular function
Cellular component
  • integral component of membrane
  • membrane
  • endosome
  • plasma membrane
  • cytoplasmic vesicle
  • late endosome membrane
  • membrane raft
  • cellular component
Biological process
  • lipid transport
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9399

69106

Ensembl

ENSG00000067221

ENSMUSG00000032333

UniProt

Q9UBI4

Q8CI66

RefSeq (mRNA)
NM_001256672
NM_001256673
NM_001256674
NM_001256675
NM_001256676

NM_001256677
NM_004809
NM_001324226
NM_001324227
NM_001324228
NM_001324229
NM_001324230

NM_026942

RefSeq (protein)
NP_001243601
NP_001243602
NP_001243603
NP_001243604
NP_001243605

NP_001243606
NP_001311155
NP_001311156
NP_001311157
NP_001311158
NP_001311159
NP_004800

NP_081218

Location (UCSC)Chr 15: 73.98 – 73.99 MbChr 9: 58.16 – 58.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Stomatin-like protein 1 is a protein that in humans is encoded by the STOML1 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000067221 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032333 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Seidel G, Prohaska R (Feb 1999). "Molecular cloning of hSLP-1, a novel human brain-specific member of the band 7/MEC-2 family similar to Caenorhabditis elegans UNC-24". Gene. 225 (1–2): 23–9. doi:10.1016/S0378-1119(98)00532-0. PMID 9931417.
  6. ^ "Entrez Gene: STOML1 stomatin (EPB72)-like 1".

Further reading

  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Price MP, Thompson RJ, Eshcol JO, et al. (2005). "Stomatin modulates gating of acid-sensing ion channels". J. Biol. Chem. 279 (51): 53886–91. doi:10.1074/jbc.M407708200. PMID 15471860.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gilles F, Glenn M, Goy A, et al. (2000). "A novel gene STORP (STOmatin-Related Protein) is localized 2 kb upstream of the promyelocytic gene on chromosome 15q22". Eur. J. Haematol. 64 (2): 104–13. doi:10.1034/j.1600-0609.2000.90054.x. PMID 10997330. S2CID 32917148.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


  • v
  • t
  • e