Solasulfone
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IUPAC name Tetrasodium 3,3'-[sulfonylbis(benzene-4,1-diylimino)]bis(1-phenylpropane-1,3-disulfonate) | |
Other names Solapsone; Sulfetrone | |
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ECHA InfoCard | 100.004.652 |
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Properties | |
Chemical formula | C30H28N2Na4O14S5 |
Molar mass | 892.81 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Solasulfone is an antileprotic drug developed from the parent compound sulphetrone.[1] It was first described and evaluated in the 1930s and 1940s as an antibacterial agent for the treatment of tuberculosis and various other infections, and later found to be effective in the treatment of leprosy.[2]
References
- ^ Chemistry for Pharmacy and the Life Sciences (1996, Pearson Education Limited) Thomas, Gareth; ppg. 349-350
- ^ Brownlee, George; Green, A. F.; Woodbine, M. (March 1948). "Sulphetrone*: A Chemotherapeutic Agent for Tuberculosis: Pharmacology and Chemotherapy". British Journal of Pharmacology and Chemotherapy. 3 (1): 15–28. doi:10.1111/j.1476-5381.1948.tb00348.x. PMC 1509804. PMID 18904720.
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Antimycobacterials, including tuberculosis treatment and leprostatic agents (J04)
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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