TMC3

Protein-coding gene in the species Homo sapiens
TMC3
Identifiers
AliasesTMC3, transmembrane channel like 3
External IDsOMIM: 617196; MGI: 2669033; HomoloGene: 45588; GeneCards: TMC3; OMA:TMC3 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for TMC3
Genomic location for TMC3
Band15q25.1Start81,331,088 bp[1]
End81,374,213 bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for TMC3
Genomic location for TMC3
Band7|7 D3Start83,234,135 bp[2]
End83,274,822 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • right uterine tube

  • right lobe of liver

  • muscle layer of sigmoid colon

  • duodenum

  • placenta

  • prefrontal cortex

  • primary visual cortex

  • gonad

  • olfactory zone of nasal mucosa
Top expressed in
  • embryo

  • basilar part of occipital bone

  • secondary oocyte

  • petrous part of the temporal bone

  • bone marrow

  • ganglionic eminence

  • sphenoid bone

  • zygote

  • primary oocyte

  • zone of skin
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • ion channel activity
  • mechanosensitive ion channel activity
Cellular component
  • membrane
  • integral component of membrane
  • integral component of plasma membrane
Biological process
  • ion transport
  • ion transmembrane transport
  • transmembrane transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

342125

233424

Ensembl

ENSG00000188869

ENSMUSG00000038540

UniProt

Q7Z5M5

Q7TQ69

RefSeq (mRNA)

NM_001080532
NM_181841

NM_177695

RefSeq (protein)

NP_001074001

NP_808363

Location (UCSC)Chr 15: 81.33 – 81.37 MbChr 7: 83.23 – 83.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane channel like 3 is a protein that in humans is encoded by the TMC3 gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188869 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038540 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Transmembrane channel like 3". Retrieved 2016-12-01.

Further reading


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