UBXN6
Protein-coding gene in the species Homo sapiens
UBXN6 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | UBXN6, UBXD1, UBXDC2, UBX domain protein 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 611946; MGI: 1913780; HomoloGene: 11538; GeneCards: UBXN6; OMA:UBXN6 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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UBX domain protein 6 is a protein in humans that is encoded by the UBXN6 gene.[5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000167671 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019578 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: UBX domain protein 6".
Further reading
- Stapf C, Cartwright E, Bycroft M, Hofmann K, Buchberger A (November 2011). "The general definition of the p97/valosin-containing protein (VCP)-interacting motif (VIM) delineates a new family of p97 cofactors". The Journal of Biological Chemistry. 286 (44): 38670–8. doi:10.1074/jbc.M111.274472. PMC 3207395. PMID 21896481.
- Nagahama M, Ohnishi M, Kawate Y, Matsui T, Miyake H, Yuasa K, Tani K, Tagaya M, Tsuji A (May 2009). "UBXD1 is a VCP-interacting protein that is involved in ER-associated degradation". Biochemical and Biophysical Research Communications. 382 (2): 303–8. doi:10.1016/j.bbrc.2009.03.012. PMID 19275885.
- Falsone SF, Gesslbauer B, Rek A, Kungl AJ (July 2007). "A proteomic approach towards the Hsp90-dependent ubiquitinylated proteome". Proteomics. 7 (14): 2375–83. doi:10.1002/pmic.200600996. PMID 17623298. S2CID 29057711.
- Ritz D, Vuk M, Kirchner P, Bug M, Schütz S, Hayer A, Bremer S, Lusk C, Baloh RH, Lee H, Glatter T, Gstaiger M, Aebersold R, Weihl CC, Meyer H (August 2011). "Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations". Nature Cell Biology. 13 (9): 1116–23. doi:10.1038/ncb2301. PMC 3246400. PMID 21822278.
- Madsen L, Andersen KM, Prag S, Moos T, Semple CA, Seeger M, Hartmann-Petersen R (2008). "Ubxd1 is a novel co-factor of the human p97 ATPase". The International Journal of Biochemistry & Cell Biology. 40 (12): 2927–42. doi:10.1016/j.biocel.2008.06.008. PMID 18656546.
- Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ (September 2008). "UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover". Cell. 134 (5): 804–16. doi:10.1016/j.cell.2008.06.048. PMC 2614663. PMID 18775313.
- Kern M, Fernandez-Sáiz V, Schäfer Z, Buchberger A (March 2009). "UBXD1 binds p97 through two independent binding sites". Biochemical and Biophysical Research Communications. 380 (2): 303–7. doi:10.1016/j.bbrc.2009.01.076. PMID 19174149.
- Carim-Todd L, Escarceller M, Estivill X, Sumoy L (January 2001). "Identification and characterization of UBXD1, a novel UBX domain-containing gene on human chromosome 19p13, and its mouse ortholog". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1517 (2): 298–301. doi:10.1016/s0167-4781(00)00248-7. PMID 11342112.
External links
- Overview of all the structural information available in the PDB for UniProt: Q9BZV1 (UBX domain-containing protein 6) at the PDBe-KB.
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