WDR24

Protein-coding gene in the species Homo sapiens
WDR24
Identifiers
AliasesWDR24, C16orf21, JFP7, WD repeat domain 24
External IDsMGI: 2446285; HomoloGene: 6870; GeneCards: WDR24; OMA:WDR24 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for WDR24
Genomic location for WDR24
Band16p13.3Start684,622 bp[1]
End690,444 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for WDR24
Genomic location for WDR24
Band17|17 A3.3Start26,042,601 bp[2]
End26,047,704 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • apex of heart

  • right hemisphere of cerebellum

  • gonad

  • gastrocnemius muscle

  • stromal cell of endometrium

  • muscle of thigh

  • right adrenal gland

  • left testis

  • right testis
Top expressed in
  • spermatocyte

  • otolith organ

  • utricle

  • spermatid

  • granulocyte

  • medullary collecting duct

  • renal corpuscle

  • hand

  • otic vesicle

  • epiblast
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
Cellular component
  • GATOR2 complex
  • lysosome
  • lysosomal membrane
  • membrane
Biological process
  • cellular response to amino acid starvation
  • regulation of autophagy
  • autophagy
  • positive regulation of TOR signaling
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84219

268933

Ensembl

ENSG00000127580

ENSMUSG00000025737

UniProt

Q96S15

Q8CFJ9

RefSeq (mRNA)

NM_032259

NM_173741

RefSeq (protein)

NP_115635

NP_776102

Location (UCSC)Chr 16: 0.68 – 0.69 MbChr 17: 26.04 – 26.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

WD repeat-containing protein 24 is a protein that in humans is encoded by the WDR24 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000127580 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025737 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ^ "Entrez Gene: WDR24 WD repeat domain 24".

Further reading

  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.


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