ZFYVE19

Protein-coding gene in the species Homo sapiens
ZFYVE19
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

1WFK, 2D8V

Identifiers
AliasesZFYVE19, ANCHR, MPFYVE, zinc finger FYVE-type containing 19, PFIC9
External IDsMGI: 1919258; HomoloGene: 12435; GeneCards: ZFYVE19; OMA:ZFYVE19 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for ZFYVE19
Genomic location for ZFYVE19
Band15q15.1Start40,807,086 bp[1]
End40,815,084 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for ZFYVE19
Genomic location for ZFYVE19
Band2|2 E5Start119,039,098 bp[2]
End119,047,530 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • mucosa of transverse colon

  • C1 segment

  • granulocyte

  • apex of heart

  • right lobe of liver

  • minor salivary glands

  • right uterine tube

  • right hemisphere of cerebellum

  • gonad

  • gallbladder
Top expressed in
  • crypt of lieberkuhn of small intestine

  • genital tubercle

  • fetal liver hematopoietic progenitor cell

  • proximal tubule

  • right kidney

  • yolk sac

  • spermatocyte

  • transitional epithelium of urinary bladder

  • tail of embryo

  • duodenum
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • phosphatidylinositol-3-phosphate binding
  • metal ion binding
  • lipid binding
Cellular component
  • cytoplasm
  • microtubule organizing center
  • centrosome
  • cleavage furrow
  • cytoskeleton
  • midbody
  • Flemming body
Biological process
  • cell cycle
  • negative regulation of cytokinesis
  • abscission
  • cell division
  • mitotic cytokinesis checkpoint signaling
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84936

72008

Ensembl

ENSG00000166140

ENSMUSG00000068580

UniProt

Q96K21

Q9DAZ9

RefSeq (mRNA)

NM_001077268
NM_001258420
NM_001258421
NM_032850

NM_001164827
NM_028054

RefSeq (protein)

NP_001070736
NP_001245349
NP_001245350
NP_116239

NP_001158299
NP_082330

Location (UCSC)Chr 15: 40.81 – 40.82 MbChr 2: 119.04 – 119.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger FYVE domain-containing protein 19 is a protein that in humans is encoded by the ZFYVE19 gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166140 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068580 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZFYVE19 zinc finger, FYVE domain containing 19".

Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Chinwalla V, Chien A, Odero M, et al. (2003). "A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15". Oncogene. 22 (9): 1400–10. doi:10.1038/sj.onc.1206273. hdl:10171/19622. PMID 12618766.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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  • 1wfk: FYVE domain of FYVE domain containing 19 protein from Mus musculus
    1wfk: FYVE domain of FYVE domain containing 19 protein from Mus musculus


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