ZNF23

Protein-coding gene in the species Homo sapiens
ZNF23
Identifiers
AliasesZNF23, KOX16, ZNF359, ZNF612, Zfp612, zinc finger protein 23
External IDsOMIM: 194527; MGI: 2443465; HomoloGene: 27083; GeneCards: ZNF23; OMA:ZNF23 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for ZNF23
Genomic location for ZNF23
Band16q22.2Start71,447,597 bp[1]
End71,463,095 bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for ZNF23
Genomic location for ZNF23
Band8|8 D3Start110,806,378 bp[2]
End110,819,373 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gonad

  • pituitary gland

  • anterior pituitary

  • right uterine tube

  • ganglionic eminence

  • cerebellar hemisphere

  • sural nerve

  • testicle

  • right hemisphere of cerebellum

  • hypothalamus
Top expressed in
  • pontine nuclei

  • Rostral migratory stream

  • ventral tegmental area

  • medial vestibular nucleus

  • paraventricular nucleus of hypothalamus

  • lateral hypothalamus

  • substantia nigra

  • dorsal tegmental nucleus

  • dorsomedial hypothalamic nucleus

  • arcuate nucleus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • metal ion binding
  • nucleic acid binding
  • protein binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7571

234725

Ensembl

ENSG00000167377

ENSMUSG00000044676

UniProt

P17027

n/a

RefSeq (mRNA)

NM_145911
NM_001304492
NM_001304493
NM_001304494

NM_175480

RefSeq (protein)
NP_001291421
NP_001291422
NP_001291423
NP_666016
NP_001368894

NP_001368895
NP_001368896
NP_001368897
NP_001368898
NP_001368899
NP_001368900
NP_001368901
NP_001368902
NP_001368903
NP_001368904
NP_001368905
NP_001368906
NP_001368907
NP_001368908
NP_001368909
NP_001368910
NP_001368913

n/a

Location (UCSC)Chr 16: 71.45 – 71.46 MbChr 8: 110.81 – 110.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 23 is a protein that in humans is encoded by the ZNF23 gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167377 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044676 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZNF23 zinc finger protein 23 (KOX 16)".

Further reading

  • Huang C, Jia Y, Yang S, et al. (2007). "Characterization of ZNF23, a KRAB-containing protein that is downregulated in human cancers and inhibits cell cycle progression". Exp. Cell Res. 313 (2): 254–63. doi:10.1016/j.yexcr.2006.10.009. PMID 17137575.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Zhou L, Zhu C, Luo K, et al. (2002). "Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development". Biochem. Biophys. Res. Commun. 295 (4): 862–8. doi:10.1016/S0006-291X(02)00759-3. PMID 12127974.
  • Cannizzaro LA, Aronson MM, Thiesen HJ (1993). "Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24". Hum. Genet. 91 (4): 383–5. doi:10.1007/BF00217362. PMID 8500793. S2CID 26273171.
  • Abrink M, Aveskogh M, Hellman L (1995). "Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937". DNA Cell Biol. 14 (2): 125–36. doi:10.1089/dna.1995.14.125. PMID 7865130.
  • Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.


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