ZNF331

Protein-coding gene in the species Homo sapiens
ZNF331
Identifiers
AliasesZNF331, RITA, ZNF361, ZNF463, zinc finger protein 331
External IDsOMIM: 606043; HomoloGene: 41276; GeneCards: ZNF331; OMA:ZNF331 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for ZNF331
Genomic location for ZNF331
Band19q13.42Start53,519,527 bp[1]
End53,580,269 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • lower lobe of lung

  • sperm

  • anterior pituitary

  • right lung

  • left ovary

  • mucosa of paranasal sinus

  • tail of epididymis

  • beta cell

  • left uterine tube

  • right ovary
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
  • zinc ion binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • transcription, DNA-templated
  • regulation of transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55422

n/a

Ensembl

ENSG00000130844

n/a

UniProt

Q9NQX6
Q71QC5

n/a

RefSeq (mRNA)
NM_001079906
NM_001079907
NM_001253798
NM_001253799
NM_001253800

NM_001253801
NM_018555
NM_001317113
NM_001317114
NM_001317115
NM_001317116
NM_001317117
NM_001317118
NM_001317119
NM_001317120
NM_001317121

n/a

RefSeq (protein)
NP_001073375
NP_001073376
NP_001240727
NP_001240728
NP_001240729

NP_001240730
NP_001304042
NP_001304043
NP_001304044
NP_001304045
NP_001304046
NP_001304047
NP_001304048
NP_001304049
NP_001304050
NP_061025
NP_001073375.1
NP_001304050.1

n/a

Location (UCSC)Chr 19: 53.52 – 53.58 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Zinc finger protein 331 is a protein that in humans is encoded by the ZNF331 gene.[3]

Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form one family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM][3]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130844 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: ZNF331 zinc finger protein 331".

Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Meiboom M, Murua Escobar H, Winkler S, et al. (2004). "Molecular characterization and mapping of the canine KRAB zinc finger gene ZNF331". Anim. Genet. 35 (3): 262–3. doi:10.1111/j.1365-2052.2004.01146.x. PMID 15147412.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Meiboom M, Murua Escobar H, Pentimalli F, et al. (2003). "A 3.4-kbp transcript of ZNF331 is solely expressed in follicular thyroid adenomas". Cytogenet. Genome Res. 101 (2): 113–7. doi:10.1159/000074165. PMID 14610350. S2CID 22276378.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Wu H, Zhang S, Qiu W, et al. (2001). "Isolation, characterization, and mapping of a novel human KRAB zinc finger protein encoding gene ZNF463". Biochim. Biophys. Acta. 1518 (1–2): 190–3. doi:10.1016/s0167-4781(01)00172-5. PMID 11267678.
  • Rippe V, Belge G, Meiboom M, et al. (2000). "A KRAB zinc finger protein gene is the potential target of 19q13 translocation in benign thyroid tumors". Genes Chromosomes Cancer. 26 (3): 229–36. doi:10.1002/(SICI)1098-2264(199911)26:3<229::AID-GCC7>3.0.CO;2-J. PMID 10502321. S2CID 25828897.


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