CXCR2 |
---|
![](//upload.wikimedia.org/wikipedia/commons/thumb/9/9b/CXCR2.png/250px-CXCR2.png) |
Visualisation de la protéine Cristallisée CXCR2 |
Structures disponibles |
---|
PDB | Recherche d'orthologue: PDBe RCSB |
---|
|
|
Identifiants |
---|
Aliases | CXCR2 |
---|
IDs externes | OMIM: 146928 MGI: 105303 HomoloGene: 10439 GeneCards: CXCR2 |
---|
Position du gène (Homme) |
---|
![Chromosome 2 humain](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 humain[1] |
---|
| Locus | 2q35 | Début | 218,125,289 bp[1] |
---|
Fin | 218,137,251 bp[1] |
---|
|
Position du gène (Souris) |
---|
![Chromosome 1 (souris)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (souris)[2] |
---|
| Locus | 1 C3|1 38.41 cM | Début | 74,193,148 bp[2] |
---|
Fin | 74,200,405 bp[2] |
---|
|
Expression génétique |
---|
Bgee | Humain | Souris (orthologue) |
---|
Fortement exprimé dans | - sang
- ligament alvéolo-dentaire
- granulocyte
- os spongieux
- epithelium of esophagus
- monocyte
- gonade
- rate
- cavité buccale
- moelle osseuse
|
| Fortement exprimé dans | - granulocyte
- placenta
- moelle osseuse
- œsophage
- embryon
- rate
- embryon
- blastocyste
- lèvre
- poumon
|
| Plus de données d'expression de référence |
|
---|
BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PBB_GE_IL8RB_207008_at_fs.png/250px-PBB_GE_IL8RB_207008_at_fs.png) | Plus de données d'expression de référence |
|
---|
|
Gene Ontology |
---|
Fonction moléculaire | - C-X-C chemokine receptor activity
- interleukin-8 binding
- liaison protéique
- interleukin-8 receptor activity
- chemokine receptor activity
- signal transducer activity
- G protein-coupled receptor activity
- C-C chemokine receptor activity
- chemokine binding
- C-C chemokine binding
| Composant cellulaire | - integral component of membrane
- membrane
- mast cell granule
- membrane plasmique
- integral component of plasma membrane
- intracellulaire
- surface cellulaire
- secretory granule membrane
- external side of plasma membrane
| Processus biologique | - neutrophil activation
- internalisation de récepteur
- dendritic cell chemotaxis
- chimiotaxie
- cellular defense response
- phospholipase C-activating G protein-coupled receptor signaling pathway
- cell surface receptor signaling pathway
- positive regulation of cell population proliferation
- réponse inflammatoire
- chemokine-mediated signaling pathway
- neutrophil degranulation
- G protein-coupled receptor signaling pathway
- acute inflammatory response to antigenic stimulus
- positive regulation of leukocyte chemotaxis
- positive regulation of cytosolic calcium ion concentration
- positive regulation of cardiac muscle cell apoptotic process
- neutrophil chemotaxis
- midbrain development
- negative regulation of neutrophil apoptotic process
- negative regulation of apoptotic process
- positive regulation of vascular permeability
- positive regulation of angiogenesis
- metanephric tubule morphogenesis
- positive regulation of neutrophil chemotaxis
- transduction de signal
- interleukin-8-mediated signaling pathway
- réponse immunitaire
- calcium-mediated signaling
- cell chemotaxis
| Sources:Amigo / QuickGO |
|
Orthologues |
---|
Espèces | Homme | Souris |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protéine) | | |
---|
Localisation (UCSC) | Chr 2: 218.13 – 218.14 Mb | Chr 1: 74.19 – 74.2 Mb |
---|
Publication PubMed | [3] | [4] |
---|
|
Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
|