S1PR1 |
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Struktur yang tersedia |
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PDB | Pencarian Ortolog: PDBe RCSB |
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Daftar kode id PDB |
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3V2W, 3V2Y |
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Pengidentifikasi |
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Alias | S1PR1, CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1, sphingosine-1-phosphate receptor 1 |
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ID eksternal | OMIM: 601974 MGI: 1096355 HomoloGene: 1071 GeneCards: S1PR1 |
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Lokasi gen (Tikus) |
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| Kr. | Kromosom 3 (tikus)[1] |
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| Pita | 3|3 G1 | Awal | 115,504,082 bp[1] |
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Akhir | 115,508,721 bp[1] |
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Pola ekspresi RNA |
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| Referensi data ekspresi selengkapnya |
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Ontologi gen |
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Fungsi molekuler | • sphingolipid binding • sphingosine-1-phosphate receptor activity • G protein-coupled receptor activity • signal transducer activity • G protein-coupled receptor binding • GO:0001948, GO:0016582 Ikatan protein plasma
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Komponen seluler | • komponen integral membran • endosom • membran • intrinsic component of plasma membrane • Membran sel • membrane raft • external side of plasma membrane • nucleoplasm • intracellular membrane-bounded organelle
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Proses biologis | • actin cytoskeleton reorganization • T cell migration • G protein-coupled receptor signaling pathway • heart trabecula morphogenesis • positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • sphingosine-1-phosphate receptor signaling pathway • positive regulation of cell migration • regulation of bone mineralization • transmission of nerve impulse • chemotaxis • positive regulation of positive chemotaxis • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • brain development • regulation of cell adhesion • Adhesi sel • Angiogenesis • neuron differentiation • positive regulation of cell population proliferation • endothelial cell differentiation • negative regulation of stress fiber assembly • regulation of bone resorption • Migrasi sel • GO:0072468 signal transduction • lamellipodium assembly • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • cardiac muscle tissue growth involved in heart morphogenesis • positive regulation of smooth muscle cell proliferation • blood vessel maturation • leukocyte chemotaxis • cytokine-mediated signaling pathway
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Sumber:Amigo / QuickGO |
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Ortolog |
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Spesies | Manusia | Tikus |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lokasi (UCSC) | n/a | Chr 3: 115.5 – 115.51 Mb |
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Pencarian PubMed | [2] | [3] |
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Wikidata |
Lihat/Sunting Manusia | Lihat/Sunting Tikus |
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