CTCF |
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사용 가능한 구조 |
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PDB | 동원체 검색: PDBe RCSB |
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식별자 |
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다른 이름 | CTCF, MRD21, CCCTC-binding factor, FAP108, CFAP108 |
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외부 ID | OMIM: 604167 MGI: 109447 HomoloGene: 4786 GeneCards: CTCF |
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유전자 위치 (쥐) |
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| 염색체 | 8번 염색체 (쥐)[2] |
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| 자리 | 8|8 D3 | 시작 | 105,636,568 bp[2] |
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끝 | 105,682,922 bp[2] |
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RNA 발현 패턴 |
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Bgee | 인간 | 쥐(동원체) |
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최상위 발현 | - ventricular zone
- ganglionic eminence
- 가슴샘
- cerebellar vermis
- paraflocculus of cerebellum
- 림프절
- 해면뼈
- Skeletal muscle tissue of rectus abdominis
- 골수
- skin of thigh
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| 최상위 발현 | - Rostral migratory stream
- 가슴샘
- neural layer of retina
- tail of embryo
- 구형낭
- genital tubercle
- otic placode
- ventricular zone
- otic vesicle
- 위판
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| 추가 참조 발현 데이터 |
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BioGPS | | 추가 참조 발현 데이터 |
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유전자 온톨로지 |
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분자 함수 | - DNA 결합
- transcription corepressor activity
- DNA-binding transcription factor activity
- zinc ion binding
- 금속 이온 결합
- chromatin insulator sequence binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- 단백질 결합
- nucleic acid binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- sequence-specific DNA binding
- DNA-binding transcription activator activity, RNA polymerase II-specific
- chromatin binding
| 세포 성분 | - 핵질
- 염색체
- 핵소체
- 동원체
- condensed chromosome
- 세포핵
| 생물학적 과정 | - DNA를 주형으로 한 전사의 조절
- regulation of gene expression, epigenetic
- regulation of centromeric sister chromatid cohesion
- chromosome segregation
- DNA를 주형으로 한 전사
- positive regulation of transcription, DNA-templated
- negative regulation of transcription, DNA-templated
- protein localization to chromosome, centromeric region
- negative regulation of cell population proliferation
- chromatin organization
- negative regulation of transcription by RNA polymerase II
- positive regulation of gene expression
- DNA 메틸화
- regulation of gene expression by genetic imprinting
- maintenance of DNA methylation
- negative regulation of gene expression
- regulation of histone methylation
- regulation of histone acetylation
- positive regulation of transcription by RNA polymerase II
| 출처: Amigo / QuickGO |
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동원체 |
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종 | 인간 | 쥐 |
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앙트레 | | |
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앙상블 | | |
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유니프롯 | | |
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RefSeq (mRNA) | |
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NM_001191022 NM_006565 NM_001363916 |
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RefSeq(단백질) | |
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NP_001177951 NP_006556 NP_001350845 |
| NP_851839 NP_001345853 NP_001390652 NP_001390653 NP_001390654
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NP_001390655 NP_001390656 NP_001390657 NP_001390658 NP_001390659 NP_001390660 NP_001390661 |
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위치(UCSC) | Chr 16: 67.56 – 67.64 Mb | Chr 8: 105.64 – 105.68 Mb |
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PubMed 검색 | [3] | [4] |
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위키데이터 |
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