Serin-tRNK ligaza
| Serin-tRNK ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.1.1.11 | ||||||||
| CAS broj | 9023-48-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Serin-tRNK ligaza (EC 6.1.1.11, seril-tRNK sintetaza, SerRS, seril-transfer ribonukleat sintetaza, seril-transfer RNK sintetaza, seril-transfer ribonukleinska kiselina sintetaza, serin translase) je enzim sa sistematskim imenom L-serin:tRNKSer ligaza (formira AMP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + L-serin + tRNKSer AMP + difosfat + L-seril-tRNKSer
Ovaj enzim takođe prepoznaje tRNKSec, specijalnu tRNK za selenocistein.
Reference
- ^ Katze, J.R. & Konigsberg, W. (1970). „Purification and properties of seryl transfer ribonucleic acid synthetase from Escherichia coli”. J. Biol. Chem. 245: 923—930. PMID 4906848.
- ^ Makman, M.H. & Cantoni, G.L. (1965). „Isolation of seryl and phenylalanyl ribonucleic acid synthetases from baker's yeast”. Biochemistry. 4: 1434—1442.
- ^ Webster, L.T. & Davie, E.W. (1961). „Purification and properties of serine-activating enzyme from beef pancreas”. J. Biol. Chem. 236: 479—484. PMID 13783661.
- ^ Ohama, T., Yang, D.C. and Hatfield, D.L. (1994). „Selenocysteine tRNA and serine tRNA are aminoacylated by the same synthetase, but may manifest different identities with respect to the long extra arm”. Arch. Biochem. Biophys. 315: 293—301. PMID 7986071. CS1 одржавање: Вишеструка имена: списак аутора (веза)
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- Serine---tRNA+ligase на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- Glutamin sintetaza
- Ubikvitinska ligaza
- Kulin
- Von Hipel–Lindau tumor supresor
- UBE3A
- Mdm2
- Kompleks promovisanja anafaze
- UBR1
- Glutationska sintetaza
- CTP sintaza
- Adenilosukcinatna sintaza
- Argininosukcinatna sintaza
- Holokarboksilazna sintaza
- GMP sintaza
- Asparagin sintaza
- Karbamoil fosfat sintaza
- I
- II
- Glutamat-cisteinska ligaza
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