CBFB |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Protein_CBFB_PDB_1cl3.png/250px-Protein_CBFB_PDB_1cl3.png) |
Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1CL3, 1E50, 1H9D, 4N9F | | |
Ідентифікатори |
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Символи | CBFB, PEBP2B, core-binding factor, beta subunit, core-binding factor beta subunit, core-binding factor subunit beta |
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Зовнішні ІД | OMIM: 121360 MGI: 99851 HomoloGene: 11173 GeneCards: CBFB |
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Онтологія гена |
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Молекулярна функція | • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001105 transcription coactivator activity • GO:0001948, GO:0016582 protein binding • DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0001104 transcription coregulator activity • sequence-specific DNA binding |
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Клітинна компонента | • клітинне ядро • мембрана • нуклеоплазма • core-binding factor complex |
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Біологічний процес | • definitive hemopoiesis • myeloid cell differentiation • protein polyubiquitination • cell maturation • transcription by RNA polymerase II • осифікація • osteoblast differentiation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • lymphocyte differentiation • regulation of cytokine-mediated signaling pathway • regulation of Wnt signaling pathway • regulation of intracellular estrogen receptor signaling pathway • regulation of regulatory T cell differentiation • regulation of keratinocyte differentiation • regulation of myeloid cell differentiation • regulation of megakaryocyte differentiation • regulation of B cell receptor signaling pathway • regulation of hematopoietic stem cell differentiation • regulation of bicellular tight junction assembly • transcription initiation from RNA polymerase II promoter • GO:1901227 negative regulation of transcription by RNA polymerase II • negative regulation of CD4-positive, alpha-beta T cell differentiation • positive regulation of CD8-positive, alpha-beta T cell differentiation |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/PBB_GE_CBFB_206788_s_at_fs.png/250px-PBB_GE_CBFB_206788_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/1/1a/PBB_GE_CBFB_202370_s_at_fs.png/250px-PBB_GE_CBFB_202370_s_at_fs.png) |
Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | NM_001755 NM_022845 NM_001368707 NM_001368708 NM_001368709
| NM_001368710 |
| | NM_001161456 NM_001161457 NM_001161458 NM_022309 |
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RefSeq (білок) | NP_001746 NP_074036 NP_001355636 NP_001355637 NP_001355638
| NP_001355639 |
| | NP_001154928 NP_001154929 NP_001154930 NP_071704 |
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Локус (UCSC) | Хр. 16: 67.03 – 67.1 Mb | Хр. 8: 105.9 – 105.94 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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