CXCL10 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/4/47/PDB_1o7z_EBI.jpg/250px-PDB_1o7z_EBI.jpg) |
Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1O80, 1LV9, 1O7Y, 1O7Z | | |
Ідентифікатори |
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Символи | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10 |
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Зовнішні ІД | OMIM: 147310 MGI: 1352450 HomoloGene: 1203 GeneCards: CXCL10 |
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Онтологія гена |
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Молекулярна функція | • cytokine activity • heparin binding • CXCR3 chemokine receptor binding • chemokine activity • GO:0001948, GO:0016582 protein binding • cAMP-dependent protein kinase regulator activity • signaling receptor binding • chemoattractant activity |
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Клітинна компонента | • extracellular region • external side of plasma membrane • міжклітинний простір • внутрішньоклітинний |
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Біологічний процес | • regulation of endothelial tube morphogenesis • negative regulation of myoblast differentiation • cellular response to heat • response to vitamin D • positive regulation of cell migration • T cell chemotaxis • chemokine-mediated signaling pathway • cell-cell signaling • response to virus • muscle organ development • positive regulation of monocyte chemotaxis • positive regulation of release of sequestered calcium ion into cytosol • endothelial cell activation • positive regulation of cAMP-mediated signaling • regulation of T cell chemotaxis • кровообіг • хемотаксис • positive regulation of leukocyte chemotaxis • cell surface receptor signaling pathway • response to lipopolysaccharide • negative regulation of myoblast fusion • defense response to virus • regulation of cell population proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь • positive regulation of cell population proliferation • response to auditory stimulus • negative regulation of angiogenesis • response to cold • cellular response to lipopolysaccharide • response to gamma radiation • positive regulation of T cell migration • GO:0072468 сигнальна трансдукція • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • regulation of protein kinase activity • defense response • inflammatory response • antimicrobial humoral immune response mediated by antimicrobial peptide • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • cytokine-mediated signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • response to bacterium • neutrophil chemotaxis • leukocyte chemotaxis • positive chemotaxis • regulation of apoptotic process |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/0/06/PBB_GE_CXCL10_204533_at_fs.png/250px-PBB_GE_CXCL10_204533_at_fs.png) |
Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | |
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RefSeq (білок) | | |
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Локус (UCSC) | Хр. 4: 76.02 – 76.02 Mb | Хр. 5: 92.49 – 92.5 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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