HFE

• peptide antigen binding
• beta-2-microglobulin binding
• co-receptor binding
• GO:0001948, GO:0016582 protein binding
• transferrin receptor binding
• signaling receptor binding
• natural killer cell lectin-like receptor binding

• integral component of membrane
• recycling endosome
• HFE-transferrin receptor complex
• мембрана
• basal part of cell
• клітинна мембрана
• apical part of cell
• integral component of plasma membrane
• terminal web
• early endosome
• MHC class I protein complex
• perinuclear region of cytoplasm
• GO:0016023 cytoplasmic vesicle
• external side of plasma membrane
• міжклітинний простір

• negative regulation of T cell antigen processing and presentation
• positive regulation of peptide hormone secretion
• positive regulation of receptor-mediated endocytosis
• cellular response to iron ion
• antigen processing and presentation
• negative regulation of receptor binding
• regulation of protein localization to cell surface
• antigen processing and presentation of peptide antigen via MHC class I
• жіноча вагітність
• positive regulation of pathway-restricted SMAD protein phosphorylation
• response to iron ion starvation
• iron ion homeostasis
• negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
• ion transport
• BMP signaling pathway
• cellular response to iron ion starvation
• response to iron ion
• multicellular organismal iron ion homeostasis
• positive regulation of ferrous iron binding
• positive regulation of transferrin receptor binding
• positive regulation of signaling receptor activity
• liver regeneration
• GO:1901313 positive regulation of gene expression
• negative regulation of T cell cytokine production
• acute-phase response
• negative regulation of proteasomal ubiquitin-dependent protein catabolic process
• negative regulation of ubiquitin-dependent protein catabolic process
• positive regulation of receptor binding
• negative regulation of signaling receptor activity
• positive regulation of protein binding
• hormone biosynthetic process
• negative regulation of CD8-positive, alpha-beta T cell activation
• cellular iron ion homeostasis
• iron ion import across plasma membrane
• transferrin transport
• GO:0034622 protein-containing complex assembly
• T cell mediated cytotoxicity
• GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь
• natural killer cell activation
• natural killer cell mediated cytotoxicity
• susceptibility to natural killer cell mediated cytotoxicity
• GO:1900400 regulation of iron ion transport