| SOX6 |
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| Ідентифікатори |
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| Символи | SOX6, HSSOXD, SRY-box 6, SRY-box transcription factor 6, TOLCAS |
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| Зовнішні ІД | OMIM: 607257 MGI: 98368 HomoloGene: 22631 GeneCards: SOX6 |
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| Пов'язані генетичні захворювання |
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| остеопороз, ожиріння[1] |
| Онтологія гена |
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| Молекулярна функція | • DNA binding
• sequence-specific DNA binding
• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• GO:0001948, GO:0016582 protein binding
• protein heterodimerization activity
• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
• GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
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| Клітинна компонента | • нуклеоплазма
• клітинне ядро
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| Біологічний процес | • cellular response to transforming growth factor beta stimulus
• cell fate commitment
• GO:0009373 regulation of transcription, DNA-templated
• cardiac muscle cell differentiation
• muscle organ development
• oligodendrocyte differentiation
• in utero embryonic development
• GO:1901227 negative regulation of transcription by RNA polymerase II
• post-embryonic development
• transcription, DNA-templated
• positive regulation of mesenchymal stem cell differentiation
• multicellular organism development
• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated
• oligodendrocyte cell fate specification
• muscle cell differentiation
• cartilage development
• astrocyte differentiation
• positive regulation of cartilage development
• positive regulation of chondrocyte differentiation
• GO:0000767 cell morphogenesis
• регуляція експресії генів
• erythrocyte differentiation
• GO:0045996 negative regulation of transcription, DNA-templated
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• erythrocyte development
• negative regulation of cardiac muscle cell differentiation
• кровотворення
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| Джерела:Amigo / QuickGO | |
| Ортологи |
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| Види | Людина | Миша |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (мРНК) | NM_033326
NM_001145811
NM_001145819
NM_017508
NM_001367872
| | NM_001367873 |
| NM_001025559
NM_001025560
NM_001277326
NM_001277327
NM_001277328
| | NM_011445 |
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| RefSeq (білок) | NP_001139283
NP_001139291
NP_059978
NP_201583
NP_001354801
| | NP_001354802 |
| NP_001020730
NP_001020731
NP_001264255
NP_001264256
NP_001264257
| | NP_035575 |
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| Локус (UCSC) | Хр. 11: 15.97 – 16.74 Mb | Хр. 7: 115.47 – 116.04 Mb |
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| PubMed search | [2] | [3] |
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| Вікідані |
| Див./Ред. для людей | Див./Ред. для мишей |
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