HOMER2 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/0/0a/Protein_HOMER2_PDB_1i7a.png/250px-Protein_HOMER2_PDB_1i7a.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | HOMER2, ACPD, CPD, HOMER-2, VESL-2, DFNA68, homer scaffolding protein 2, homer scaffold protein 2 |
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External IDs | OMIM: 604799; MGI: 1347354; HomoloGene: 3560; GeneCards: HOMER2; OMA:HOMER2 - orthologs |
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Gene location (Human) |
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![Chromosome 15 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/07/Ideogram_human_chromosome_15.svg/300px-Ideogram_human_chromosome_15.svg.png) | Chr. | Chromosome 15 (human)[1] |
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| Band | 15q25.2 | Start | 82,836,946 bp[1] |
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End | 82,986,153 bp[1] |
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Gene location (Mouse) |
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![Chromosome 7 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png) | Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 D3 | Start | 81,250,229 bp[2] |
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End | 81,357,275 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - body of pancreas
- olfactory zone of nasal mucosa
- muscle of thigh
- minor salivary glands
- gastrocnemius muscle
- islet of Langerhans
- Skeletal muscle tissue of rectus abdominis
- skin of leg
- parotid gland
- skin of abdomen
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| Top expressed in | - lacrimal gland
- parotid gland
- transitional epithelium of urinary bladder
- lateral septal nucleus
- substantia nigra
- Region I of hippocampus proper
- crypt of lieberkuhn of small intestine
- epithelium of stomach
- olfactory epithelium
- trigeminal ganglion
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d2/PBB_GE_HOMER2_217080_s_at_fs.png/250px-PBB_GE_HOMER2_217080_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- protein homodimerization activity
- protein domain specific binding
- synaptic receptor adaptor activity
- actin binding
- G protein-coupled glutamate receptor binding
- glutamate receptor binding
- protein heterodimerization activity
| Cellular component | - cytoplasm
- neuronal cell body
- postsynaptic membrane
- dendrite
- synapse
- postsynaptic density
- membrane
- apical part of cell
- stereocilium tip
- cell projection
- stereocilium
- plasma membrane
- cell junction
- cytosol
- glutamatergic synapse
- neuron projection
| Biological process | - G protein-coupled glutamate receptor signaling pathway
- chemical homeostasis within a tissue
- behavioral response to cocaine
- regulation of G protein-coupled receptor signaling pathway
- hearing
- calcium-mediated signaling using intracellular calcium source
- negative regulation of interleukin-2 production
- negative regulation of calcineurin-NFAT signaling cascade
- regulation of store-operated calcium entry
- positive regulation of signal transduction
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_004839 NM_199330 NM_199331 NM_199332 |
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NM_001164086 NM_001164087 NM_011983 NM_177029 |
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RefSeq (protein) | | |
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NP_001157558 NP_001157559 NP_036113 |
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Location (UCSC) | Chr 15: 82.84 – 82.99 Mb | Chr 7: 81.25 – 81.36 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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