RRP8 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | RRP8, KIAA0409, NML, ribosomal RNA processing 8, methyltransferase, homolog (yeast), ribosomal RNA processing 8 |
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External IDs | OMIM: 615818; MGI: 1914251; HomoloGene: 5621; GeneCards: RRP8; OMA:RRP8 - orthologs |
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Gene location (Human) |
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![Chromosome 11 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png) | Chr. | Chromosome 11 (human)[1] |
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| Band | 11p15.4 | Start | 6,595,072 bp[1] |
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End | 6,603,616 bp[1] |
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Gene location (Mouse) |
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![Chromosome 7 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png) | Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 E3 | Start | 105,380,937 bp[2] |
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End | 105,386,592 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - muscle layer of sigmoid colon
- right lobe of liver
- gonad
- mucosa of transverse colon
- popliteal artery
- tibial arteries
- ventricular zone
- granulocyte
- body of uterus
- right auricle
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| Top expressed in | - zygote
- genital tubercle
- tail of embryo
- primitive streak
- epiblast
- ureter
- embryo
- primary oocyte
- embryo
- secondary oocyte
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/e/ec/PBB_GE_KIAA0409_203170_at_fs.png/250px-PBB_GE_KIAA0409_203170_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/b/bd/PBB_GE_KIAA0409_203171_s_at_fs.png/250px-PBB_GE_KIAA0409_203171_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - methyltransferase activity
- transferase activity
- S-adenosylmethionine-dependent methyltransferase activity
- methylated histone binding
- protein binding
- RNA binding
| Cellular component | - plasma membrane
- nucleoplasm
- rDNA heterochromatin
- chromatin silencing complex
- nucleolus
- nucleus
- cytosol
| Biological process | - cellular response to glucose starvation
- regulation of transcription, DNA-templated
- regulation of transcription by glucose
- transcription, DNA-templated
- methylation
- rDNA heterochromatin assembly
- intrinsic apoptotic signaling pathway by p53 class mediator
- rRNA processing
- chromatin organization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 11: 6.6 – 6.6 Mb | Chr 7: 105.38 – 105.39 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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