Rufloxacin
Chemical compound
- J01MA10 (WHO)
- In general: ℞ (Prescription only)
- 9-Fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic acid
- 101363-10-4 Y 106017-08-7
- 58258
- 52489 N
- Y521XM2900
- ChEMBL295619 N
- DTXSID6048412
- Interactive image
- CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F
InChI
- InChI=1S/C17H18FN3O3S/c1-19-2-4-20(5-3-19)14-12(18)8-10-13-16(14)25-7-6-21(13)9-11(15(10)22)17(23)24/h8-9H,2-7H2,1H3,(H,23,24) N
- Key:NJCJBUHJQLFDSW-UHFFFAOYSA-N N
Rufloxacin is a quinolone antibiotic.[1] It is sold under the brand names, Ruflox, Monos, Qari, Tebraxin, Uroflox, Uroclar.
See also
- Quinolones
References
- ^ Rafalsky V, Andreeva I, Rjabkova E (July 2006). "Quinolones for uncomplicated acute cystitis in women". The Cochrane Database of Systematic Reviews. 3 (3): CD003597. doi:10.1002/14651858.CD003597.pub2. PMC 7003573. PMID 16856014.
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(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor | |||||||||
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Sulfonamides (DHPS inhibitor) |
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Combinations |
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Other DHPS inhibitors |
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation | |||||||||
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Fluoroquinolones |
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Newer non-fluorinated | |||||||||
Related (DG) |
inhibitors
Nitroimidazole derivatives |
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Rifamycins/ RNA polymerase | |
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Lipiarmycins |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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